Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NFE2L3Nuclear factor, erythroid 2 like 3. (667 aa)    
Predicted Functional Partners:
MAFF
MAF bZIP transcription factor F.
    
 0.892
NFE2
Nuclear factor, erythroid 2.
  
 
0.862
NFE2L1
Nuclear factor, erythroid 2 like 1.
    
 
0.801
NOC3L
Nucleolar complex protein 3 homolog.
    
   0.747
KEAP1
Kelch like ECH associated protein 1.
    
 0.737
CUL3
Cullin 3; Belongs to the cullin family.
    
 0.721
GSK3A
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
   
 0.694
GSK3B
Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.
   
 0.694
DCAF11
DDB1- and CUL4-associated factor 11; May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex; Belongs to the WD repeat LEC14B family.
    
 0.675
MAFB
MAF bZIP transcription factor B.
    
 0.671
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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