| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AICDA | CDA | ENSOCUP00000022572 | ENSOCUP00000013963 | Activation induced cytidine deaminase. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.705 |
| AICDA | SMUG1 | ENSOCUP00000022572 | ENSOCUP00000023115 | Activation induced cytidine deaminase. | Single-strand-selective monofunctional uracil-DNA glycosylase 1. | 0.575 |
| AICDA | TDG | ENSOCUP00000022572 | ENSOCUP00000035383 | Activation induced cytidine deaminase. | Thymine DNA glycosylase. | 0.692 |
| AICDA | UNG | ENSOCUP00000022572 | ENSOCUP00000002732 | Activation induced cytidine deaminase. | Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family. | 0.838 |
| APEX1 | FEN1 | ENSOCUP00000004349 | ENSOCUP00000002851 | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.993 |
| APEX1 | LIG1 | ENSOCUP00000004349 | ENSOCUP00000010183 | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. | DNA ligase. | 0.950 |
| APEX1 | OGG1 | ENSOCUP00000004349 | ENSOCUP00000013733 | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. | OGG_N domain-containing protein. | 0.930 |
| APEX1 | SMUG1 | ENSOCUP00000004349 | ENSOCUP00000023115 | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. | Single-strand-selective monofunctional uracil-DNA glycosylase 1. | 0.776 |
| APEX1 | TDG | ENSOCUP00000004349 | ENSOCUP00000035383 | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. | Thymine DNA glycosylase. | 0.852 |
| APEX1 | UNG | ENSOCUP00000004349 | ENSOCUP00000002732 | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. | Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family. | 0.812 |
| CDA | AICDA | ENSOCUP00000013963 | ENSOCUP00000022572 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Activation induced cytidine deaminase. | 0.705 |
| CDA | SMUG1 | ENSOCUP00000013963 | ENSOCUP00000023115 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Single-strand-selective monofunctional uracil-DNA glycosylase 1. | 0.677 |
| CDA | UNG | ENSOCUP00000013963 | ENSOCUP00000002732 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family. | 0.779 |
| DCAF1 | DDB1 | ENSOCUP00000008904 | ENSOCUP00000001429 | DDB1 and CUL4 associated factor 1. | Damage specific DNA binding protein 1. | 0.999 |
| DCAF1 | SMUG1 | ENSOCUP00000008904 | ENSOCUP00000023115 | DDB1 and CUL4 associated factor 1. | Single-strand-selective monofunctional uracil-DNA glycosylase 1. | 0.457 |
| DCAF1 | UNG | ENSOCUP00000008904 | ENSOCUP00000002732 | DDB1 and CUL4 associated factor 1. | Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family. | 0.846 |
| DDB1 | DCAF1 | ENSOCUP00000001429 | ENSOCUP00000008904 | Damage specific DNA binding protein 1. | DDB1 and CUL4 associated factor 1. | 0.999 |
| DDB1 | FEN1 | ENSOCUP00000001429 | ENSOCUP00000002851 | Damage specific DNA binding protein 1. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.832 |
| DDB1 | LIG1 | ENSOCUP00000001429 | ENSOCUP00000010183 | Damage specific DNA binding protein 1. | DNA ligase. | 0.788 |
| DDB1 | OGG1 | ENSOCUP00000001429 | ENSOCUP00000013733 | Damage specific DNA binding protein 1. | OGG_N domain-containing protein. | 0.574 |