TRIB2 protein (Oryctolagus cuniculus) - STRING interaction network

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Predicted Interactions

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Score

TRIB2

Tribbles pseudokinase 2. (343 aa)

Predicted Functional Partners:

COP1

0.745

AKT2

0.700

AKT3

0.700

PRKAB1

0.683

PRKAB2

0.683

MAP2K1

0.618

STK40

0.612

RIBC2

0.609

CEBPA

0.609

PRKAG1

0.586

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT2	AKT3	ENSOCUP00000000339	ENSOCUP00000041212	AKT serine/threonine kinase 2.	Non-specific serine/threonine protein kinase.	0.429
AKT2	MAP2K1	ENSOCUP00000000339	ENSOCUP00000029057	AKT serine/threonine kinase 2.	Dual specificity mitogen-activated protein kinase kinase 1; Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Binding of extracellular ligands such as growth factors, cytokines and hormones to their cell-surface receptors activates RAS and this initiates RAF1 activation. RAF1 then further activates the dual-specificity protein kinases MAP2K1/MEK1 and MAP2K2/MEK2. Both MAP2K1/MEK1 and MAP2K2/MEK2 function specifically in the MAPK/ERK cascade, and catalyze the concomitant phosphorylation of a threonine and a tyrosine resid [...]	0.572
AKT2	STK40	ENSOCUP00000000339	ENSOCUP00000004618	AKT serine/threonine kinase 2.	Serine/threonine kinase 40.	0.423
AKT2	TRIB2	ENSOCUP00000000339	ENSOCUP00000002738	AKT serine/threonine kinase 2.	Tribbles pseudokinase 2.	0.700
AKT3	AKT2	ENSOCUP00000041212	ENSOCUP00000000339	Non-specific serine/threonine protein kinase.	AKT serine/threonine kinase 2.	0.429
AKT3	MAP2K1	ENSOCUP00000041212	ENSOCUP00000029057	Non-specific serine/threonine protein kinase.	Dual specificity mitogen-activated protein kinase kinase 1; Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Binding of extracellular ligands such as growth factors, cytokines and hormones to their cell-surface receptors activates RAS and this initiates RAF1 activation. RAF1 then further activates the dual-specificity protein kinases MAP2K1/MEK1 and MAP2K2/MEK2. Both MAP2K1/MEK1 and MAP2K2/MEK2 function specifically in the MAPK/ERK cascade, and catalyze the concomitant phosphorylation of a threonine and a tyrosine resid [...]	0.411
AKT3	STK40	ENSOCUP00000041212	ENSOCUP00000004618	Non-specific serine/threonine protein kinase.	Serine/threonine kinase 40.	0.428
AKT3	TRIB2	ENSOCUP00000041212	ENSOCUP00000002738	Non-specific serine/threonine protein kinase.	Tribbles pseudokinase 2.	0.700
CEBPA	TRIB2	ENSOCUP00000022073	ENSOCUP00000002738	CCAAT enhancer binding protein alpha.	Tribbles pseudokinase 2.	0.609
COP1	STK40	ENSOCUP00000004743	ENSOCUP00000004618	COP1 E3 ubiquitin ligase.	Serine/threonine kinase 40.	0.743
COP1	TRIB2	ENSOCUP00000004743	ENSOCUP00000002738	COP1 E3 ubiquitin ligase.	Tribbles pseudokinase 2.	0.745
MAP2K1	AKT2	ENSOCUP00000029057	ENSOCUP00000000339	Dual specificity mitogen-activated protein kinase kinase 1; Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Binding of extracellular ligands such as growth factors, cytokines and hormones to their cell-surface receptors activates RAS and this initiates RAF1 activation. RAF1 then further activates the dual-specificity protein kinases MAP2K1/MEK1 and MAP2K2/MEK2. Both MAP2K1/MEK1 and MAP2K2/MEK2 function specifically in the MAPK/ERK cascade, and catalyze the concomitant phosphorylation of a threonine and a tyrosine resid [...]	AKT serine/threonine kinase 2.	0.572
MAP2K1	AKT3	ENSOCUP00000029057	ENSOCUP00000041212	Dual specificity mitogen-activated protein kinase kinase 1; Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Binding of extracellular ligands such as growth factors, cytokines and hormones to their cell-surface receptors activates RAS and this initiates RAF1 activation. RAF1 then further activates the dual-specificity protein kinases MAP2K1/MEK1 and MAP2K2/MEK2. Both MAP2K1/MEK1 and MAP2K2/MEK2 function specifically in the MAPK/ERK cascade, and catalyze the concomitant phosphorylation of a threonine and a tyrosine resid [...]	Non-specific serine/threonine protein kinase.	0.411
MAP2K1	RIBC2	ENSOCUP00000029057	ENSOCUP00000014314	Dual specificity mitogen-activated protein kinase kinase 1; Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Binding of extracellular ligands such as growth factors, cytokines and hormones to their cell-surface receptors activates RAS and this initiates RAF1 activation. RAF1 then further activates the dual-specificity protein kinases MAP2K1/MEK1 and MAP2K2/MEK2. Both MAP2K1/MEK1 and MAP2K2/MEK2 function specifically in the MAPK/ERK cascade, and catalyze the concomitant phosphorylation of a threonine and a tyrosine resid [...]	RIB43A domain with coiled-coils 2.	0.422
MAP2K1	TRIB2	ENSOCUP00000029057	ENSOCUP00000002738	Dual specificity mitogen-activated protein kinase kinase 1; Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Binding of extracellular ligands such as growth factors, cytokines and hormones to their cell-surface receptors activates RAS and this initiates RAF1 activation. RAF1 then further activates the dual-specificity protein kinases MAP2K1/MEK1 and MAP2K2/MEK2. Both MAP2K1/MEK1 and MAP2K2/MEK2 function specifically in the MAPK/ERK cascade, and catalyze the concomitant phosphorylation of a threonine and a tyrosine resid [...]	Tribbles pseudokinase 2.	0.618
PRKAB1	PRKAB2	ENSOCUP00000028658	ENSOCUP00000045892	Protein kinase AMP-activated non-catalytic subunit beta 1.	Protein kinase AMP-activated non-catalytic subunit beta 2.	0.988
PRKAB1	PRKAG1	ENSOCUP00000028658	ENSOCUP00000030557	Protein kinase AMP-activated non-catalytic subunit beta 1.	Uncharacterized protein.	0.999
PRKAB1	STK40	ENSOCUP00000028658	ENSOCUP00000004618	Protein kinase AMP-activated non-catalytic subunit beta 1.	Serine/threonine kinase 40.	0.604
PRKAB1	TRIB2	ENSOCUP00000028658	ENSOCUP00000002738	Protein kinase AMP-activated non-catalytic subunit beta 1.	Tribbles pseudokinase 2.	0.683
PRKAB2	PRKAB1	ENSOCUP00000045892	ENSOCUP00000028658	Protein kinase AMP-activated non-catalytic subunit beta 2.	Protein kinase AMP-activated non-catalytic subunit beta 1.	0.988