STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DOCK8Dedicator of cytokinesis 8; Belongs to the DOCK family. (2102 aa)    
Predicted Functional Partners:
CDC42-2
Uncharacterized protein.
   
 0.969
CDC42
Uncharacterized protein.
   
 0.968
WAS
WASP actin nucleation promoting factor.
   
  
 0.809
RAC2
Rac family small GTPase 2.
   
 0.785
LRCH1
Leucine rich repeats and calponin homology domain containing 1.
   
 
 0.738
RHOJ
Ras homolog family member J.
   
 0.707
ARID4B
AT-rich interaction domain 4B.
      
 0.688
LRCH3
Leucine rich repeats and calponin homology domain containing 3.
   
 
 0.671
RHOQ
Uncharacterized protein.
   
 0.661
RHOH
Ras homolog family member H.
   
 0.652
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.