ITGA2B protein (Oryctolagus cuniculus) - STRING interaction network

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Score

ITGA2B

Integrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family. (1008 aa)

Predicted Functional Partners:

VWF

0.999

ITGB3

0.999

FN1

0.995

VTN

0.994

TLN1

0.957

THBS1

0.952

ITGB1

0.950

ITGAV

0.949

TLN2

0.944

PTK2-2

0.941

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FN1	ITGA2B	ENSOCUP00000008718	ENSOCUP00000002848	Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts (By similarity).	Integrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family.	0.995
FN1	ITGAV	ENSOCUP00000008718	ENSOCUP00000039361	Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts (By similarity).	Integrin subunit alpha V; Belongs to the integrin alpha chain family.	0.998
FN1	ITGB1	ENSOCUP00000008718	ENSOCUP00000003143	Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts (By similarity).	Integrin beta; Belongs to the integrin beta chain family.	0.999
FN1	ITGB3	ENSOCUP00000008718	ENSOCUP00000033109	Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts (By similarity).	Integrin beta; Belongs to the integrin beta chain family.	0.998
FN1	PTK2-2	ENSOCUP00000008718	ENSOCUP00000038411	Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts (By similarity).	FERM_N_2 domain-containing protein.	0.779
FN1	THBS1	ENSOCUP00000008718	ENSOCUP00000003290	Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts (By similarity).	Thrombospondin 1.	0.946
FN1	TLN1	ENSOCUP00000008718	ENSOCUP00000008817	Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts (By similarity).	Talin 1.	0.886
FN1	TLN2	ENSOCUP00000008718	ENSOCUP00000011268	Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts (By similarity).	Talin 2.	0.762
FN1	VTN	ENSOCUP00000008718	ENSOCUP00000024132	Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts (By similarity).	Vitronectin; Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway.	0.996
FN1	VWF	ENSOCUP00000008718	ENSOCUP00000023792	Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts (By similarity).	Von Willebrand factor.	0.979
ITGA2B	FN1	ENSOCUP00000002848	ENSOCUP00000008718	Integrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family.	Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts (By similarity).	0.995
ITGA2B	ITGAV	ENSOCUP00000002848	ENSOCUP00000039361	Integrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family.	Integrin subunit alpha V; Belongs to the integrin alpha chain family.	0.949
ITGA2B	ITGB1	ENSOCUP00000002848	ENSOCUP00000003143	Integrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family.	Integrin beta; Belongs to the integrin beta chain family.	0.950
ITGA2B	ITGB3	ENSOCUP00000002848	ENSOCUP00000033109	Integrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family.	Integrin beta; Belongs to the integrin beta chain family.	0.999
ITGA2B	PTK2-2	ENSOCUP00000002848	ENSOCUP00000038411	Integrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family.	FERM_N_2 domain-containing protein.	0.941
ITGA2B	THBS1	ENSOCUP00000002848	ENSOCUP00000003290	Integrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family.	Thrombospondin 1.	0.952
ITGA2B	TLN1	ENSOCUP00000002848	ENSOCUP00000008817	Integrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family.	Talin 1.	0.957
ITGA2B	TLN2	ENSOCUP00000002848	ENSOCUP00000011268	Integrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family.	Talin 2.	0.944
ITGA2B	VTN	ENSOCUP00000002848	ENSOCUP00000024132	Integrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family.	Vitronectin; Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway.	0.994
ITGA2B	VWF	ENSOCUP00000002848	ENSOCUP00000023792	Integrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family.	Von Willebrand factor.	0.999