STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZFP36ZFP36 ring finger protein. (338 aa)    
Predicted Functional Partners:
MAPKAPK2
MAP kinase-activated protein kinase 2; Stress-activated serine/threonine-protein kinase involved in cytokine production, endocytosis, reorganization of the cytoskeleton, cell migration, cell cycle control, chromatin remodeling, DNA damage response and transcriptional regulation. Following stress, it is phosphorylated and activated by MAP kinase p38-alpha/MAPK14, leading to phosphorylation of substrates. Phosphorylates serine in the peptide sequence, Hyd-X-R-X(2)-S, where Hyd is a large hydrophobic residue. Phosphorylates ALOX5, CDC25B, CDC25C, CEP131, ELAVL1, HNRNPA0, HSP27/HSPB1, KRT1 [...]
    
 0.987
EXOSC8
Exosome component 8.
   
  0.970
CNOT1
CCR4-NOT transcription complex subunit 1.
    
 0.949
XRN1
5'-3' exoribonuclease 1.
    
 0.944
DCP2
Decapping mRNA 2.
   
 0.887
DUSP1
Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.
   
 
 0.818
TIA1
TIA1 cytotoxic granule associated RNA binding protein.
    
 
 0.742
FOS
Fos proto-oncogene, AP-1 transcription factor subunit.
   
  
 0.712
DCP1A
Decapping mRNA 1A.
    
 0.705
G1TRX8_RABIT
Uncharacterized protein.
    
 0.701
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.