RERGL protein (Oryctolagus cuniculus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

RERGL

RERG like. (249 aa)

Predicted Functional Partners:

ITSN2

0.881

ITSN1

0.766

LOC100346323

0.700

MET

0.600

MST1R

0.600

MUSTN1

0.599

G1TY13_RABIT

0.590

ENSOCUP00000043565

0.590

OTOP2

0.570

SLC12A9

0.547

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSOCUP00000043565	RERGL	ENSOCUP00000043565	ENSOCUP00000003019	SAM domain-containing protein.	RERG like.	0.590
G1TY13_RABIT	RERGL	ENSOCUP00000021972	ENSOCUP00000003019	PDZ domain-containing protein.	RERG like.	0.590
ITSN1	ITSN2	ENSOCUP00000047769	ENSOCUP00000019448	Intersectin 1.	Intersectin 2.	0.952
ITSN1	RERGL	ENSOCUP00000047769	ENSOCUP00000003019	Intersectin 1.	RERG like.	0.766
ITSN2	ITSN1	ENSOCUP00000019448	ENSOCUP00000047769	Intersectin 2.	Intersectin 1.	0.952
ITSN2	MET	ENSOCUP00000019448	ENSOCUP00000003111	Intersectin 2.	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	0.896
ITSN2	MST1R	ENSOCUP00000019448	ENSOCUP00000008078	Intersectin 2.	Macrophage stimulating 1 receptor.	0.896
ITSN2	MUSTN1	ENSOCUP00000019448	ENSOCUP00000038355	Intersectin 2.	Uncharacterized protein.	0.505
ITSN2	RERGL	ENSOCUP00000019448	ENSOCUP00000003019	Intersectin 2.	RERG like.	0.881
LOC100346323	MET	ENSOCUP00000015500	ENSOCUP00000003111	Uncharacterized protein.	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	0.687
LOC100346323	MST1R	ENSOCUP00000015500	ENSOCUP00000008078	Uncharacterized protein.	Macrophage stimulating 1 receptor.	0.687
LOC100346323	MUSTN1	ENSOCUP00000015500	ENSOCUP00000038355	Uncharacterized protein.	Uncharacterized protein.	0.457
LOC100346323	RERGL	ENSOCUP00000015500	ENSOCUP00000003019	Uncharacterized protein.	RERG like.	0.700
MET	ITSN2	ENSOCUP00000003111	ENSOCUP00000019448	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	Intersectin 2.	0.896
MET	LOC100346323	ENSOCUP00000003111	ENSOCUP00000015500	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	Uncharacterized protein.	0.687
MET	MST1R	ENSOCUP00000003111	ENSOCUP00000008078	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	Macrophage stimulating 1 receptor.	0.715
MET	MUSTN1	ENSOCUP00000003111	ENSOCUP00000038355	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	Uncharacterized protein.	0.572
MET	RERGL	ENSOCUP00000003111	ENSOCUP00000003019	Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]	RERG like.	0.600
MST1R	ITSN2	ENSOCUP00000008078	ENSOCUP00000019448	Macrophage stimulating 1 receptor.	Intersectin 2.	0.896
MST1R	LOC100346323	ENSOCUP00000008078	ENSOCUP00000015500	Macrophage stimulating 1 receptor.	Uncharacterized protein.	0.687