STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SLFN11Schlafen family member 13. (904 aa)    
Predicted Functional Partners:
VCL
Vinculin.
    
 
 0.638
EVA1B
FAM176 domain-containing protein.
      
 0.624
SAMHD1
SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1.
   
  
 0.578
CMPK2
Cytidine/uridine monophosphate kinase 2.
   
  
 0.552
TOP1
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...]
    
 
 0.544
MOB3C
MOB kinase activator 3C.
      
 0.543
ABHD14B
Abhydrolase domain containing 14B.
      
 0.529
RPA3
Replication protein A3.
   
  
 0.492
SERGEF
Secretion regulating guanine nucleotide exchange factor.
    
 
 0.491
REL
REL proto-oncogene, NF-kB subunit.
      
 0.489
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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