Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TMC5Transmembrane channel-like protein. (938 aa)    
Predicted Functional Partners:
KCNH8
Potassium voltage-gated channel subfamily H member 8.
   
 
 0.685
TMEM211
Uncharacterized protein.
     
 0.680
TMEM132E
Transmembrane protein 132E.
     
 0.656
TMEM171
Transmembrane protein 171.
      
 0.593
CNGA1
Cyclic nucleotide gated channel subunit alpha 1.
      
 0.591
GPR137C
G protein-coupled receptor 137C.
      
 0.581
CLCNKA
Chloride channel protein ClC-Ka; Voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume; membrane potential stabilization, signal transduction and transepithelial transport. May be important in urinary concentrating mechanisms; Belongs to the chloride channel (TC 2.A.49) family. CLCNKA subfamily.
      
 0.572
UNC119
Unc-119 lipid binding chaperone.
      
 0.569
IQCG
IQ motif containing G.
    
 
 0.563
RASL12
RAS like family 12.
    
 0.517
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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