| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CREB1 | PRKACB | ENSOCUP00000004708 | ENSOCUP00000043583 | cAMP responsive element binding protein 1. | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. | 0.975 |
| LIPE | PRKACB | ENSOCUP00000000016 | ENSOCUP00000043583 | Lipase E, hormone sensitive type. | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. | 0.974 |
| LIPE | PRKAR1A | ENSOCUP00000000016 | ENSOCUP00000014966 | Lipase E, hormone sensitive type. | Protein kinase cAMP-dependent type I regulatory subunit alpha. | 0.687 |
| LIPE | PRKAR1B | ENSOCUP00000000016 | ENSOCUP00000027549 | Lipase E, hormone sensitive type. | Cyclic nucleotide-binding domain-containing protein. | 0.687 |
| LIPE | PRKAR2A | ENSOCUP00000000016 | ENSOCUP00000024499 | Lipase E, hormone sensitive type. | Protein kinase cAMP-dependent type II regulatory subunit alpha. | 0.882 |
| LIPE | PRKAR2B | ENSOCUP00000000016 | ENSOCUP00000010967 | Lipase E, hormone sensitive type. | Protein kinase cAMP-dependent type II regulatory subunit beta. | 0.878 |
| PDE4D | PRKACB | ENSOCUP00000033174 | ENSOCUP00000043583 | Phosphodiesterase. | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. | 0.983 |
| PDE4D | PRKAR1A | ENSOCUP00000033174 | ENSOCUP00000014966 | Phosphodiesterase. | Protein kinase cAMP-dependent type I regulatory subunit alpha. | 0.495 |
| PDE4D | RYR2 | ENSOCUP00000033174 | ENSOCUP00000002126 | Phosphodiesterase. | Ryanodine receptor 2; Calcium channel that mediates the release of Ca(2+) from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering cardiac muscle contraction. Aberrant channel activation can lead to cardiac arrhythmia. In cardiac myocytes, calcium release is triggered by increased Ca(2+) levels due to activation of the L-type calcium channel CACNA1C. Required for cellular calcium ion homeostasis. Required for embryonic heart development (By similarity). The calcium channel activity is modulated by formation of heterotetramers with RYR3; Belongs to t [...] | 0.580 |
| PKIA | PRKACB | ENSOCUP00000018622 | ENSOCUP00000043583 | cAMP-dependent protein kinase inhibitor alpha; Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains; Belongs to the PKI family. | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. | 0.982 |
| PRKACB | CREB1 | ENSOCUP00000043583 | ENSOCUP00000004708 | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. | cAMP responsive element binding protein 1. | 0.975 |
| PRKACB | LIPE | ENSOCUP00000043583 | ENSOCUP00000000016 | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. | Lipase E, hormone sensitive type. | 0.974 |
| PRKACB | PDE4D | ENSOCUP00000043583 | ENSOCUP00000033174 | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. | Phosphodiesterase. | 0.983 |
| PRKACB | PKIA | ENSOCUP00000043583 | ENSOCUP00000018622 | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. | cAMP-dependent protein kinase inhibitor alpha; Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains; Belongs to the PKI family. | 0.982 |
| PRKACB | PRKAR1A | ENSOCUP00000043583 | ENSOCUP00000014966 | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. | Protein kinase cAMP-dependent type I regulatory subunit alpha. | 0.993 |
| PRKACB | PRKAR1B | ENSOCUP00000043583 | ENSOCUP00000027549 | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. | Cyclic nucleotide-binding domain-containing protein. | 0.976 |
| PRKACB | PRKAR2A | ENSOCUP00000043583 | ENSOCUP00000024499 | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. | Protein kinase cAMP-dependent type II regulatory subunit alpha. | 0.994 |
| PRKACB | PRKAR2B | ENSOCUP00000043583 | ENSOCUP00000010967 | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. | Protein kinase cAMP-dependent type II regulatory subunit beta. | 0.996 |
| PRKACB | RYR2 | ENSOCUP00000043583 | ENSOCUP00000002126 | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. | Ryanodine receptor 2; Calcium channel that mediates the release of Ca(2+) from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering cardiac muscle contraction. Aberrant channel activation can lead to cardiac arrhythmia. In cardiac myocytes, calcium release is triggered by increased Ca(2+) levels due to activation of the L-type calcium channel CACNA1C. Required for cellular calcium ion homeostasis. Required for embryonic heart development (By similarity). The calcium channel activity is modulated by formation of heterotetramers with RYR3; Belongs to t [...] | 0.986 |
| PRKACB | SMO | ENSOCUP00000043583 | ENSOCUP00000027051 | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. | Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. | 0.985 |
