Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RSPO3R-spondin 3. (279 aa)    
Predicted Functional Partners:
LGR4
Leucine rich repeat containing G protein-coupled receptor 4.
   
 0.992
LGR5
Leucine rich repeat containing G protein-coupled receptor 5.
   
 0.985
RNF43
RING-type domain-containing protein.
    
 0.967
ZNRF3
Zinc and ring finger 3.
    
 0.964
LGR6
Leucine rich repeat containing G protein-coupled receptor 6.
    
 0.947
RSPO4
Uncharacterized protein.
     
0.894
RSPO1
Uncharacterized protein.
  
  
0.867
RSPO2
R-spondin 2.
  
  
0.750
WRN
WRN RecQ like helicase.
  
  
 0.724
WNT3A
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.
      
 0.708
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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