STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RSPO3R-spondin 3. (279 aa)    
Predicted Functional Partners:
LGR4
Leucine rich repeat containing G protein-coupled receptor 4.
   
 0.996
RNF43
RING-type domain-containing protein.
   
 0.988
ZNRF3
Zinc and ring finger 3.
   
 0.979
LGR5
Leucine rich repeat containing G protein-coupled receptor 5.
   
 0.939
LGR6
Leucine rich repeat containing G protein-coupled receptor 6.
    
 0.747
WRN
WRN RecQ like helicase.
  
  
 0.722
WNT3A
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.
   
  
 0.715
NOG
Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.
      
 0.696
PTPRK
Protein tyrosine phosphatase receptor type K.
   
 
 0.666
AXIN2
Axin 2.
   
  
 0.653
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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