Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SLIT1Slit guidance ligand 1. (1452 aa)    
Predicted Functional Partners:
ROBO2
Roundabout guidance receptor 2.
   
 0.995
ROBO1
Roundabout guidance receptor 1.
   
 0.994
ROBO4
Roundabout guidance receptor 4.
   
 0.960
ROBO3
Roundabout guidance receptor 3.
    
 0.887
NTN1
Netrin 1.
    
 0.766
SEMA3A
Semaphorin 3A; Belongs to the semaphorin family.
   
  
 0.691
DRAXIN
Draxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway.
      
 0.666
SEMA4F
Ssemaphorin 4F; Belongs to the semaphorin family.
      
 0.646
PLXNA1
Plexin A1.
   
 0.638
NEO1
Neogenin 1.
   
 0.620
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
Server load: low (18%) [HD]