TLR10 protein (Oryctolagus cuniculus) - STRING interaction network

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TLR10

TIR domain-containing protein; Belongs to the Toll-like receptor family. (810 aa)

Predicted Functional Partners:

MYD88

0.962

TIRAP

0.891

TLR4

0.781

TLR9

0.766

TOLLIP

0.764

CD14

0.749

NFKB1

0.709

HSPA4

0.676

TICAM2

0.674

HSPD1

0.672

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CD14	HSPD1	ENSOCUP00000003648	ENSOCUP00000010958	Monocyte differentiation antigen CD14; Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell su [...]	Uncharacterized protein; Belongs to the chaperonin (HSP60) family.	0.408
CD14	TLR10	ENSOCUP00000003648	ENSOCUP00000003207	Monocyte differentiation antigen CD14; Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell su [...]	TIR domain-containing protein; Belongs to the Toll-like receptor family.	0.749
CD14	TLR4	ENSOCUP00000003648	ENSOCUP00000001909	Monocyte differentiation antigen CD14; Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell su [...]	TIR domain-containing protein; Belongs to the Toll-like receptor family.	0.974
CD14	TLR9	ENSOCUP00000003648	ENSOCUP00000047700	Monocyte differentiation antigen CD14; Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell su [...]	TIR domain-containing protein.	0.481
HSPA4	HSPD1	ENSOCUP00000007228	ENSOCUP00000010958	Heat shock protein family A (Hsp70) member 4.	Uncharacterized protein; Belongs to the chaperonin (HSP60) family.	0.942
HSPA4	TLR10	ENSOCUP00000007228	ENSOCUP00000003207	Heat shock protein family A (Hsp70) member 4.	TIR domain-containing protein; Belongs to the Toll-like receptor family.	0.676
HSPA4	TLR4	ENSOCUP00000007228	ENSOCUP00000001909	Heat shock protein family A (Hsp70) member 4.	TIR domain-containing protein; Belongs to the Toll-like receptor family.	0.521
HSPD1	CD14	ENSOCUP00000010958	ENSOCUP00000003648	Uncharacterized protein; Belongs to the chaperonin (HSP60) family.	Monocyte differentiation antigen CD14; Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell su [...]	0.408
HSPD1	HSPA4	ENSOCUP00000010958	ENSOCUP00000007228	Uncharacterized protein; Belongs to the chaperonin (HSP60) family.	Heat shock protein family A (Hsp70) member 4.	0.942
HSPD1	TLR10	ENSOCUP00000010958	ENSOCUP00000003207	Uncharacterized protein; Belongs to the chaperonin (HSP60) family.	TIR domain-containing protein; Belongs to the Toll-like receptor family.	0.672
HSPD1	TLR4	ENSOCUP00000010958	ENSOCUP00000001909	Uncharacterized protein; Belongs to the chaperonin (HSP60) family.	TIR domain-containing protein; Belongs to the Toll-like receptor family.	0.944
MYD88	NFKB1	ENSOCUP00000034296	ENSOCUP00000023734	Uncharacterized protein.	Nuclear factor kappa B subunit 1.	0.889
MYD88	TICAM2	ENSOCUP00000034296	ENSOCUP00000016017	Uncharacterized protein.	TIR domain-containing protein.	0.733
MYD88	TIRAP	ENSOCUP00000034296	ENSOCUP00000032284	Uncharacterized protein.	TIR domain containing adaptor protein.	0.998
MYD88	TLR10	ENSOCUP00000034296	ENSOCUP00000003207	Uncharacterized protein.	TIR domain-containing protein; Belongs to the Toll-like receptor family.	0.962
MYD88	TLR4	ENSOCUP00000034296	ENSOCUP00000001909	Uncharacterized protein.	TIR domain-containing protein; Belongs to the Toll-like receptor family.	0.997
MYD88	TLR9	ENSOCUP00000034296	ENSOCUP00000047700	Uncharacterized protein.	TIR domain-containing protein.	0.994
MYD88	TOLLIP	ENSOCUP00000034296	ENSOCUP00000018327	Uncharacterized protein.	Toll interacting protein.	0.965
NFKB1	MYD88	ENSOCUP00000023734	ENSOCUP00000034296	Nuclear factor kappa B subunit 1.	Uncharacterized protein.	0.889
NFKB1	TIRAP	ENSOCUP00000023734	ENSOCUP00000032284	Nuclear factor kappa B subunit 1.	TIR domain containing adaptor protein.	0.433