STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
METAP1DMethionine aminopeptidase; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val). (468 aa)    
Predicted Functional Partners:
IYD
Iodotyrosine deiodinase.
  
 
 0.894
ETFB
Electron transfer flavoprotein subunit beta.
  
 
 0.882
FDX1
2Fe-2S ferredoxin-type domain-containing protein.
  
 
 0.850
ETFA
Electron transfer flavoprotein subunit alpha.
   
 
 0.829
SLCO3A1
Solute carrier organic anion transporter family member.
      
 0.696
CRYL1
Lambda-crystallin; Functions as crystallin in the rabbit eye lens. Has high L- gulonate 3-dehydrogenase activity.
  
 
 0.693
HADH
Hydroxyacyl-CoA dehydrogenase.
  
 
 0.693
SLC15A3
Solute carrier family 15 member 3.
      
 0.669
GSR
Glutathione-disulfide reductase.
  
  
 0.645
H6PD
GDH/6PGL endoplasmic bifunctional protein; Bifunctional enzyme localized in the lumen of the endoplasmic reticulum that catalyzes the first two steps of the oxidative branch of the pentose phosphate pathway/shunt, an alternative to glycolysis and a major source of reducing power and metabolic intermediates for biosynthetic processes. Has a hexose-6-phosphate dehydrogenase activity, with broad substrate specificity compared to glucose-6- phosphate 1-dehydrogenase/G6PD, and catalyzes the first step of the pentose phosphate pathway. In addition, acts as a 6- phosphogluconolactonase and ca [...]
  
  
 0.637
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.