SPOCK3 protein (Oryctolagus cuniculus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

SPOCK3

SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3. (344 aa)

Predicted Functional Partners:

GH1

0.622

CST8

0.544

MMP16

0.496

SH2D4A

0.483

RAB3IL1

0.483

C2CD2

0.465

GTDC1

0.465

FSTL4

0.450

DENND5B

0.432

SMOC1

0.430

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C2CD2	GTDC1	ENSOCUP00000013330	ENSOCUP00000048125	C2 calcium dependent domain containing 2.	Uncharacterized protein.	0.695
C2CD2	SPOCK3	ENSOCUP00000013330	ENSOCUP00000003235	C2 calcium dependent domain containing 2.	SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3.	0.465
CST8	SPOCK3	ENSOCUP00000025718	ENSOCUP00000003235	Cystatin 8.	SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3.	0.544
DENND5B	FSTL4	ENSOCUP00000034291	ENSOCUP00000024523	DENN domain containing 5B.	Follistatin like 4.	0.566
DENND5B	SH2D4A	ENSOCUP00000034291	ENSOCUP00000014256	DENN domain containing 5B.	SH2 domain containing 4A.	0.617
DENND5B	SPOCK3	ENSOCUP00000034291	ENSOCUP00000003235	DENN domain containing 5B.	SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3.	0.432
FSTL4	DENND5B	ENSOCUP00000024523	ENSOCUP00000034291	Follistatin like 4.	DENN domain containing 5B.	0.566
FSTL4	SH2D4A	ENSOCUP00000024523	ENSOCUP00000014256	Follistatin like 4.	SH2 domain containing 4A.	0.608
FSTL4	SPOCK3	ENSOCUP00000024523	ENSOCUP00000003235	Follistatin like 4.	SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3.	0.450
GH1	SPOCK3	ENSOCUP00000003753	ENSOCUP00000003235	Somatotropin; Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues; Belongs to the somatotropin/prolactin family.	SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3.	0.622
GTDC1	C2CD2	ENSOCUP00000048125	ENSOCUP00000013330	Uncharacterized protein.	C2 calcium dependent domain containing 2.	0.695
GTDC1	SPOCK3	ENSOCUP00000048125	ENSOCUP00000003235	Uncharacterized protein.	SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3.	0.465
MMP16	SPOCK3	ENSOCUP00000009663	ENSOCUP00000003235	Matrix metallopeptidase 16.	SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3.	0.496
RAB3IL1	SPOCK3	ENSOCUP00000028961	ENSOCUP00000003235	RAB3A interacting protein like 1.	SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3.	0.483
SH2D4A	DENND5B	ENSOCUP00000014256	ENSOCUP00000034291	SH2 domain containing 4A.	DENN domain containing 5B.	0.617
SH2D4A	FSTL4	ENSOCUP00000014256	ENSOCUP00000024523	SH2 domain containing 4A.	Follistatin like 4.	0.608
SH2D4A	SPOCK3	ENSOCUP00000014256	ENSOCUP00000003235	SH2 domain containing 4A.	SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3.	0.483
SMOC1	SPOCK3	ENSOCUP00000040516	ENSOCUP00000003235	SPARC related modular calcium binding 1.	SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3.	0.430
SPOCK3	C2CD2	ENSOCUP00000003235	ENSOCUP00000013330	SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3.	C2 calcium dependent domain containing 2.	0.465
SPOCK3	CST8	ENSOCUP00000003235	ENSOCUP00000025718	SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3.	Cystatin 8.	0.544