ACRBP protein (Oryctolagus cuniculus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ACRBP

Acrosin binding protein. (537 aa)

Predicted Functional Partners:

ZPBP2

0.809

ACR

0.764

ZPBP

0.696

SPACA3

0.668

PKDREJ

0.663

IZUMO1

0.660

ADAM2

0.658

AKAP3

0.657

SPACA1

0.650

ZAN

0.617

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACR	ACRBP	ENSOCUP00000018308	ENSOCUP00000003236	Acrosin heavy chain; Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome; Belongs to the peptidase S1 family.	Acrosin binding protein.	0.764
ACR	ADAM2	ENSOCUP00000018308	ENSOCUP00000046349	Acrosin heavy chain; Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome; Belongs to the peptidase S1 family.	Disintegrin and metalloproteinase domain-containing protein 2; Sperm surface membrane protein that may be involved in sperm- egg plasma membrane adhesion and fusion during fertilization. Could have a direct role in sperm-zona binding or migration of sperm from the uterus into the oviduct. Interactions with egg membrane could be mediated via binding between its disintegrin-like domain to one or more integrins receptors on the egg. This is a non catalytic metalloprotease-like protein (By similarity).	0.482
ACR	AKAP3	ENSOCUP00000018308	ENSOCUP00000001697	Acrosin heavy chain; Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome; Belongs to the peptidase S1 family.	A-kinase anchoring protein 3.	0.460
ACR	IZUMO1	ENSOCUP00000018308	ENSOCUP00000028382	Acrosin heavy chain; Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome; Belongs to the peptidase S1 family.	Ig-like domain-containing protein.	0.794
ACR	SPACA1	ENSOCUP00000018308	ENSOCUP00000011178	Acrosin heavy chain; Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome; Belongs to the peptidase S1 family.	Sperm acrosome associated 1.	0.595
ACR	SPACA3	ENSOCUP00000018308	ENSOCUP00000009286	Acrosin heavy chain; Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome; Belongs to the peptidase S1 family.	Sperm acrosome associated 3; Belongs to the glycosyl hydrolase 22 family.	0.400
ACR	ZAN	ENSOCUP00000018308	ENSOCUP00000004858	Acrosin heavy chain; Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome; Belongs to the peptidase S1 family.	Zonadhesin; Binds in a species-specific manner to the zona pellucida of the egg. May be involved in gamete recognition and/or signaling (By similarity).	0.716
ACR	ZPBP2	ENSOCUP00000018308	ENSOCUP00000040148	Acrosin heavy chain; Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome; Belongs to the peptidase S1 family.	Zona pellucida binding protein 2.	0.654
ACRBP	ACR	ENSOCUP00000003236	ENSOCUP00000018308	Acrosin binding protein.	Acrosin heavy chain; Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome; Belongs to the peptidase S1 family.	0.764
ACRBP	ADAM2	ENSOCUP00000003236	ENSOCUP00000046349	Acrosin binding protein.	Disintegrin and metalloproteinase domain-containing protein 2; Sperm surface membrane protein that may be involved in sperm- egg plasma membrane adhesion and fusion during fertilization. Could have a direct role in sperm-zona binding or migration of sperm from the uterus into the oviduct. Interactions with egg membrane could be mediated via binding between its disintegrin-like domain to one or more integrins receptors on the egg. This is a non catalytic metalloprotease-like protein (By similarity).	0.658
ACRBP	AKAP3	ENSOCUP00000003236	ENSOCUP00000001697	Acrosin binding protein.	A-kinase anchoring protein 3.	0.657
ACRBP	IZUMO1	ENSOCUP00000003236	ENSOCUP00000028382	Acrosin binding protein.	Ig-like domain-containing protein.	0.660
ACRBP	PKDREJ	ENSOCUP00000003236	ENSOCUP00000008073	Acrosin binding protein.	Polycystin family receptor for egg jelly.	0.663
ACRBP	SPACA1	ENSOCUP00000003236	ENSOCUP00000011178	Acrosin binding protein.	Sperm acrosome associated 1.	0.650
ACRBP	SPACA3	ENSOCUP00000003236	ENSOCUP00000009286	Acrosin binding protein.	Sperm acrosome associated 3; Belongs to the glycosyl hydrolase 22 family.	0.668
ACRBP	ZAN	ENSOCUP00000003236	ENSOCUP00000004858	Acrosin binding protein.	Zonadhesin; Binds in a species-specific manner to the zona pellucida of the egg. May be involved in gamete recognition and/or signaling (By similarity).	0.617
ACRBP	ZPBP	ENSOCUP00000003236	ENSOCUP00000043896	Acrosin binding protein.	Zona pellucida binding protein.	0.696
ACRBP	ZPBP2	ENSOCUP00000003236	ENSOCUP00000040148	Acrosin binding protein.	Zona pellucida binding protein 2.	0.809
ADAM2	ACR	ENSOCUP00000046349	ENSOCUP00000018308	Disintegrin and metalloproteinase domain-containing protein 2; Sperm surface membrane protein that may be involved in sperm- egg plasma membrane adhesion and fusion during fertilization. Could have a direct role in sperm-zona binding or migration of sperm from the uterus into the oviduct. Interactions with egg membrane could be mediated via binding between its disintegrin-like domain to one or more integrins receptors on the egg. This is a non catalytic metalloprotease-like protein (By similarity).	Acrosin heavy chain; Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome; Belongs to the peptidase S1 family.	0.482
ADAM2	ACRBP	ENSOCUP00000046349	ENSOCUP00000003236	Disintegrin and metalloproteinase domain-containing protein 2; Sperm surface membrane protein that may be involved in sperm- egg plasma membrane adhesion and fusion during fertilization. Could have a direct role in sperm-zona binding or migration of sperm from the uterus into the oviduct. Interactions with egg membrane could be mediated via binding between its disintegrin-like domain to one or more integrins receptors on the egg. This is a non catalytic metalloprotease-like protein (By similarity).	Acrosin binding protein.	0.658