| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BCAR1 | EGFR | ENSOCUP00000037429 | ENSOCUP00000009041 | BCAR1 scaffold protein, Cas family member. | Receptor protein-tyrosine kinase. | 0.461 |
| BCAR1 | LCK | ENSOCUP00000037429 | ENSOCUP00000003181 | BCAR1 scaffold protein, Cas family member. | Tyrosine-protein kinase. | 0.585 |
| BCAR1 | LYN | ENSOCUP00000037429 | ENSOCUP00000002661 | BCAR1 scaffold protein, Cas family member. | Tyrosine-protein kinase. | 0.780 |
| BCAR1 | PTPN22 | ENSOCUP00000037429 | ENSOCUP00000003267 | BCAR1 scaffold protein, Cas family member. | Protein tyrosine phosphatase non-receptor type 22. | 0.694 |
| BCAR1 | SHC1 | ENSOCUP00000037429 | ENSOCUP00000013916 | BCAR1 scaffold protein, Cas family member. | SHC adaptor protein 1. | 0.425 |
| CD4 | CTLA4 | ENSOCUP00000030708 | ENSOCUP00000017677 | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | Cytotoxic T-lymphocyte protein 4; Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. | 0.932 |
| CD4 | EGFR | ENSOCUP00000030708 | ENSOCUP00000009041 | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | Receptor protein-tyrosine kinase. | 0.705 |
| CD4 | LCK | ENSOCUP00000030708 | ENSOCUP00000003181 | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | Tyrosine-protein kinase. | 0.985 |
| CD4 | LYN | ENSOCUP00000030708 | ENSOCUP00000002661 | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | Tyrosine-protein kinase. | 0.825 |
| CD4 | PTPN22 | ENSOCUP00000030708 | ENSOCUP00000003267 | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | Protein tyrosine phosphatase non-receptor type 22. | 0.677 |
| CD4 | ZAP70 | ENSOCUP00000030708 | ENSOCUP00000005043 | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | Tyrosine-protein kinase. | 0.979 |
| CTLA4 | CD4 | ENSOCUP00000017677 | ENSOCUP00000030708 | Cytotoxic T-lymphocyte protein 4; Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | 0.932 |
| CTLA4 | EGFR | ENSOCUP00000017677 | ENSOCUP00000009041 | Cytotoxic T-lymphocyte protein 4; Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. | Receptor protein-tyrosine kinase. | 0.664 |
| CTLA4 | LCK | ENSOCUP00000017677 | ENSOCUP00000003181 | Cytotoxic T-lymphocyte protein 4; Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. | Tyrosine-protein kinase. | 0.772 |
| CTLA4 | LYN | ENSOCUP00000017677 | ENSOCUP00000002661 | Cytotoxic T-lymphocyte protein 4; Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. | Tyrosine-protein kinase. | 0.538 |
| CTLA4 | PTPN22 | ENSOCUP00000017677 | ENSOCUP00000003267 | Cytotoxic T-lymphocyte protein 4; Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. | Protein tyrosine phosphatase non-receptor type 22. | 0.684 |
| CTLA4 | ZAP70 | ENSOCUP00000017677 | ENSOCUP00000005043 | Cytotoxic T-lymphocyte protein 4; Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. | Tyrosine-protein kinase. | 0.718 |
| EGFR | BCAR1 | ENSOCUP00000009041 | ENSOCUP00000037429 | Receptor protein-tyrosine kinase. | BCAR1 scaffold protein, Cas family member. | 0.461 |
| EGFR | CD4 | ENSOCUP00000009041 | ENSOCUP00000030708 | Receptor protein-tyrosine kinase. | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | 0.705 |
| EGFR | CTLA4 | ENSOCUP00000009041 | ENSOCUP00000017677 | Receptor protein-tyrosine kinase. | Cytotoxic T-lymphocyte protein 4; Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28. | 0.664 |
