HIPK1 protein (Oryctolagus cuniculus) - STRING interaction network

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Score

HIPK1

Homeodomain interacting protein kinase 1. (1447 aa)

Predicted Functional Partners:

TP53

0.976

RASSF5

0.907

RITA1

0.839

DCAF7

0.819

G1U940_RABIT

0.629

PIN1

0.607

DAXX

0.562

MECP2

0.538

ARX

0.525

UBE2I

0.513

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARX	HIPK1	ENSOCUP00000024141	ENSOCUP00000003284	Aristaless related homeobox.	Homeodomain interacting protein kinase 1.	0.525
DAXX	G1U940_RABIT	ENSOCUP00000009116	ENSOCUP00000025959	Death domain associated protein.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.796
DAXX	HIPK1	ENSOCUP00000009116	ENSOCUP00000003284	Death domain associated protein.	Homeodomain interacting protein kinase 1.	0.562
DAXX	TP53	ENSOCUP00000009116	ENSOCUP00000000989	Death domain associated protein.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...]	0.992
DAXX	UBE2I	ENSOCUP00000009116	ENSOCUP00000026696	Death domain associated protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.820
DCAF7	HIPK1	ENSOCUP00000013632	ENSOCUP00000003284	DDB1 and CUL4 associated factor 7.	Homeodomain interacting protein kinase 1.	0.819
G1U940_RABIT	DAXX	ENSOCUP00000025959	ENSOCUP00000009116	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Death domain associated protein.	0.796
G1U940_RABIT	HIPK1	ENSOCUP00000025959	ENSOCUP00000003284	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Homeodomain interacting protein kinase 1.	0.629
G1U940_RABIT	PIN1	ENSOCUP00000025959	ENSOCUP00000046685	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Peptidyl-prolyl cis-trans isomerase.	0.682
G1U940_RABIT	UBE2I	ENSOCUP00000025959	ENSOCUP00000026696	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.801
HIPK1	ARX	ENSOCUP00000003284	ENSOCUP00000024141	Homeodomain interacting protein kinase 1.	Aristaless related homeobox.	0.525
HIPK1	DAXX	ENSOCUP00000003284	ENSOCUP00000009116	Homeodomain interacting protein kinase 1.	Death domain associated protein.	0.562
HIPK1	DCAF7	ENSOCUP00000003284	ENSOCUP00000013632	Homeodomain interacting protein kinase 1.	DDB1 and CUL4 associated factor 7.	0.819
HIPK1	G1U940_RABIT	ENSOCUP00000003284	ENSOCUP00000025959	Homeodomain interacting protein kinase 1.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.629
HIPK1	MECP2	ENSOCUP00000003284	ENSOCUP00000048554	Homeodomain interacting protein kinase 1.	Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).	0.538
HIPK1	PIN1	ENSOCUP00000003284	ENSOCUP00000046685	Homeodomain interacting protein kinase 1.	Peptidyl-prolyl cis-trans isomerase.	0.607
HIPK1	RASSF5	ENSOCUP00000003284	ENSOCUP00000032032	Homeodomain interacting protein kinase 1.	Ras association domain family member 5.	0.907
HIPK1	RITA1	ENSOCUP00000003284	ENSOCUP00000024079	Homeodomain interacting protein kinase 1.	RBPJ interacting and tubulin associated 1.	0.839
HIPK1	TP53	ENSOCUP00000003284	ENSOCUP00000000989	Homeodomain interacting protein kinase 1.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...]	0.976
HIPK1	UBE2I	ENSOCUP00000003284	ENSOCUP00000026696	Homeodomain interacting protein kinase 1.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.513