STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
THBS1Thrombospondin 1. (1171 aa)    
Predicted Functional Partners:
CD36
CD36 molecule; Belongs to the CD36 family.
   
 0.999
LOC100355470
Ig-like domain-containing protein.
   
 
 0.999
MMP9
Matrix metalloproteinase-9; Could play a role in bone osteoclastic resorption. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments (By similarity).
   
 0.990
ITGB1
Integrin beta; Belongs to the integrin beta chain family.
   
 0.988
ITGB3
Integrin beta; Belongs to the integrin beta chain family.
   
 0.984
ITGAV
Integrin subunit alpha V; Belongs to the integrin alpha chain family.
   
 0.966
LTBP1
Latent transforming growth factor beta binding protein 1.
   
 
 0.954
ITGA2B
Integrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family.
   
 0.952
THBS4
Thrombospondin 4.
  
0.947
FN1
Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts (By similarity).
   
 0.946
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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