Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
TAS2R4Taste receptor type 2. (297 aa)    
Predicted Functional Partners:
TAS2R3
Taste receptor type 2.
  
 
0.900
GNB3
G protein subunit beta 3.
    
 0.879
ENSOCUP00000033954
Taste receptor type 2.
     
 0.861
GNAT3
G protein subunit alpha transducin 3.
     
 0.779
ENSOCUP00000040629
Taste receptor type 2.
  
  
0.749
TAS1R1
Taste 1 receptor member 1.
     
 0.669
TAS1R2
Taste 1 receptor member 2.
     
 0.645
GNB5
Guanine nucleotide-binding protein subunit beta-5; Enhances GTPase-activating protein (GAP) activity of regulator of G protein signaling (RGS) proteins, hence involved in the termination of the signaling initiated by the G protein coupled receptors (GPCRs) by accelerating the GTP hydrolysis on the G-alpha subunits, thereby promoting their inactivation (Probable). Increases RGS9 GTPase-activating protein (GAP) activity, hence contributes to the deactivation of G protein signaling initiated by D(2) dopamine receptors (By similarity). May play an important role in neuronal signaling, incl [...]
    
 0.555
GNB4
G protein subunit beta 4.
    
 0.544
GNAT2
G protein subunit alpha transducin 2.
     
 0.544
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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