DDX10 protein (Oryctolagus cuniculus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

DDX10

RNA helicase. (872 aa)

Predicted Functional Partners:

ESF1

0.998

UTP14A

0.995

DDX18

0.991

UTP3

0.988

EIF4E

0.988

ABT1

0.987

NOM1

0.984

RRP36

0.979

EIF4G1

0.977

UTP18

0.975

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABT1	DDX10	ENSOCUP00000014117	ENSOCUP00000003333	Activator of basal transcription 1.	RNA helicase.	0.987
ABT1	DDX18	ENSOCUP00000014117	ENSOCUP00000024880	Activator of basal transcription 1.	RNA helicase.	0.960
ABT1	ESF1	ENSOCUP00000014117	ENSOCUP00000004698	Activator of basal transcription 1.	ESF1 nucleolar pre-rRNA processing protein homolog.	0.983
ABT1	NOM1	ENSOCUP00000014117	ENSOCUP00000038352	Activator of basal transcription 1.	Nucleolar protein with MIF4G domain 1.	0.959
ABT1	RRP36	ENSOCUP00000014117	ENSOCUP00000020095	Activator of basal transcription 1.	Ribosomal RNA processing 36.	0.991
ABT1	UTP14A	ENSOCUP00000014117	ENSOCUP00000013914	Activator of basal transcription 1.	Uncharacterized protein.	0.783
ABT1	UTP18	ENSOCUP00000014117	ENSOCUP00000021684	Activator of basal transcription 1.	UTP18 small subunit processome component.	0.981
ABT1	UTP3	ENSOCUP00000014117	ENSOCUP00000008613	Activator of basal transcription 1.	UTP3 small subunit processome component.	0.432
DDX10	ABT1	ENSOCUP00000003333	ENSOCUP00000014117	RNA helicase.	Activator of basal transcription 1.	0.987
DDX10	DDX18	ENSOCUP00000003333	ENSOCUP00000024880	RNA helicase.	RNA helicase.	0.991
DDX10	EIF4E	ENSOCUP00000003333	ENSOCUP00000032078	RNA helicase.	Eukaryotic translation initiation factor 4E; Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates the binding to the mRNA cap (By similarity).	0.988
DDX10	EIF4G1	ENSOCUP00000003333	ENSOCUP00000032992	RNA helicase.	Eukaryotic translation initiation factor 4 gamma 1; Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome.	0.977
DDX10	ESF1	ENSOCUP00000003333	ENSOCUP00000004698	RNA helicase.	ESF1 nucleolar pre-rRNA processing protein homolog.	0.998
DDX10	NOM1	ENSOCUP00000003333	ENSOCUP00000038352	RNA helicase.	Nucleolar protein with MIF4G domain 1.	0.984
DDX10	RRP36	ENSOCUP00000003333	ENSOCUP00000020095	RNA helicase.	Ribosomal RNA processing 36.	0.979
DDX10	UTP14A	ENSOCUP00000003333	ENSOCUP00000013914	RNA helicase.	Uncharacterized protein.	0.995
DDX10	UTP18	ENSOCUP00000003333	ENSOCUP00000021684	RNA helicase.	UTP18 small subunit processome component.	0.975
DDX10	UTP3	ENSOCUP00000003333	ENSOCUP00000008613	RNA helicase.	UTP3 small subunit processome component.	0.988
DDX18	ABT1	ENSOCUP00000024880	ENSOCUP00000014117	RNA helicase.	Activator of basal transcription 1.	0.960
DDX18	DDX10	ENSOCUP00000024880	ENSOCUP00000003333	RNA helicase.	RNA helicase.	0.991