Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PTCRAUncharacterized protein. (196 aa)    
Predicted Functional Partners:
POLR1B
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
      
 0.637
IKZF1
IKAROS family zinc finger 1.
     
 0.596
SLC5A2
Sodium/nucleoside cotransporter; Actively transports uridine into cells by Na(+) cotransport. May play a role in reabsorption of nucleosides from glomerular filtrate by the proximal tubule in kidney, and in the regulation of cardiac contractility by adenosine.
      
 0.578
NOTCH3
Notch receptor 3.
    
 0.572
RPL7L1
Uncharacterized protein.
      
 0.566
IL7R
Interleukin 7 receptor.
      
 0.563
RPL7L1-2
Uncharacterized protein.
      
 0.559
OR5I1
Olfactory receptor.
   
  
 0.558
VPREB3
V-set pre-B cell surrogate light chain 3.
      
 0.538
CD72
C-type lectin domain-containing protein.
      
 0.533
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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