Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
GNMTGlycine N-methyltransferase; Catalyzes the methylation of glycine by using S- adenosylmethionine (AdoMet) to form N-methylglycine (sarcosine) with the concomitant production of S-adenosylhomocysteine (AdoHcy). Possible crucial role in the regulation of tissue concentration of AdoMet and of metabolism of methionine. (295 aa)    
Predicted Functional Partners:
ENSOCUP00000044443
DAO domain-containing protein.
   
 
 0.974
DMGDH
Dimethylglycine dehydrogenase.
   
 
 0.964
MAT2A
S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP.
   
 
 0.954
SARDH
Uncharacterized protein.
   
 
 0.948
AHCYL1
Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family.
   
 
 0.947
MAT2B
Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine.
   
 
 0.941
AGXT
Serine--pyruvate aminotransferase.
   
 
 0.939
AHCY
Adenosylhomocysteinase; Belongs to the adenosylhomocysteinase family.
   
 
 0.935
PIPOX
Peroxisomal sarcosine oxidase; Metabolizes sarcosine, L-pipecolic acid and L-proline.
   
 
 0.924
AHCYL2
Adenosylhomocysteinase like 2.
   
 
 0.924
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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