STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CD74CD74 molecule. (375 aa)    
Predicted Functional Partners:
MIF
Macrophage migration inhibitory factor.
   
 0.999
HLA-DRA
Integral membrane protein; Belongs to the MHC class II family.
   
 0.998
CD44
CD44 molecule (Indian blood group).
   
 
 0.994
HLA-DQB2
Major histocompatibility complex, class II, DQ beta 1.
   
 0.992
HLA-DOB
Major histocompatibility complex, class II, DO beta.
   
 0.989
HLA-DMA
Major histocompatibility complex, class II, DM alpha; Belongs to the MHC class II family.
   
 0.988
LOC100349667
Ig-like domain-containing protein.
   
 0.987
CXCR2
C-X-C chemokine receptor type 2; Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2 (By similarity).
   
 
 0.985
HLA-DPB1
RLA class II histocompatibility antigen, DP beta chain.
   
 0.983
CXCR4
C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family.
   
 
 0.980
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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