Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FHDC1FH2 domain containing 1. (1142 aa)    
Predicted Functional Partners:
ARHGEF4
Uncharacterized protein.
   
 
 0.752
DIAPH1
DAD domain-containing protein.
    
 0.747
PFN4
Uncharacterized protein; Belongs to the profilin family.
    
 0.732
DVL2
Dishevelled segment polarity protein 2.
   
 0.697
FMN2
Formin 2.
    
0.697
WASL
WASP like actin nucleation promoting factor.
   
 0.692
WIPF3
WAS/WASL interacting protein family member 3.
    
 0.670
RHOF
Ras homolog family member F, filopodia associated.
    
 0.652
DVL3
Dishevelled segment polarity protein 3.
    
 0.652
PSTPIP2
Proline-serine-threonine phosphatase interacting protein 2.
    
 
 0.645
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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