STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CRYZL1Crystallin zeta like 1. (348 aa)    
Predicted Functional Partners:
URB1
URB1 ribosome biogenesis homolog.
      
 0.823
PPP1R21
Protein phosphatase 1 regulatory subunit 21.
   
   0.823
PSMG1
Proteasome assembly chaperone 1.
   
  
 0.790
BRWD1
Bromodomain and WD repeat domain containing 1.
      
 0.675
ZADH2
Zinc binding alcohol dehydrogenase domain containing 2.
  
   
 0.656
XYLB
Xylulokinase.
     
 0.634
MECR
Mitochondrial trans-2-enoyl-CoA reductase.
  
  
 0.633
TMEM242
Uncharacterized protein.
      
 0.619
MED4
Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
   
  
 0.607
GCAT
Aminotran_1_2 domain-containing protein.
    
 0.607
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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