LRIT3 protein (Oryctolagus cuniculus) - STRING interaction network

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Score

LRIT3

Leucine rich repeat, Ig-like and transmembrane domains 3. (685 aa)

Predicted Functional Partners:

TRPM1

0.898

CACNA1F

0.891

RRH

0.813

NTNG1

0.781

GRM6

0.773

ADGRL1

0.770

ADGRL3

0.770

ADGRL2

0.770

PTK7

0.767

GNB5

0.754

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADGRL1	GNB5	ENSOCUP00000023951	ENSOCUP00000010220	Adhesion G protein-coupled receptor L1; Belongs to the G-protein coupled receptor 2 family.	Guanine nucleotide-binding protein subunit beta-5; Enhances GTPase-activating protein (GAP) activity of regulator of G protein signaling (RGS) proteins, hence involved in the termination of the signaling initiated by the G protein coupled receptors (GPCRs) by accelerating the GTP hydrolysis on the G-alpha subunits, thereby promoting their inactivation (Probable). Increases RGS9 GTPase-activating protein (GAP) activity, hence contributes to the deactivation of G protein signaling initiated by D(2) dopamine receptors (By similarity). May play an important role in neuronal signaling, incl [...]	0.481
ADGRL1	LRIT3	ENSOCUP00000023951	ENSOCUP00000003394	Adhesion G protein-coupled receptor L1; Belongs to the G-protein coupled receptor 2 family.	Leucine rich repeat, Ig-like and transmembrane domains 3.	0.770
ADGRL2	GNB5	ENSOCUP00000044036	ENSOCUP00000010220	Adhesion G protein-coupled receptor L2; Belongs to the G-protein coupled receptor 2 family.	Guanine nucleotide-binding protein subunit beta-5; Enhances GTPase-activating protein (GAP) activity of regulator of G protein signaling (RGS) proteins, hence involved in the termination of the signaling initiated by the G protein coupled receptors (GPCRs) by accelerating the GTP hydrolysis on the G-alpha subunits, thereby promoting their inactivation (Probable). Increases RGS9 GTPase-activating protein (GAP) activity, hence contributes to the deactivation of G protein signaling initiated by D(2) dopamine receptors (By similarity). May play an important role in neuronal signaling, incl [...]	0.481
ADGRL2	LRIT3	ENSOCUP00000044036	ENSOCUP00000003394	Adhesion G protein-coupled receptor L2; Belongs to the G-protein coupled receptor 2 family.	Leucine rich repeat, Ig-like and transmembrane domains 3.	0.770
ADGRL3	GNB5	ENSOCUP00000030893	ENSOCUP00000010220	Adhesion G protein-coupled receptor L3; Belongs to the G-protein coupled receptor 2 family.	Guanine nucleotide-binding protein subunit beta-5; Enhances GTPase-activating protein (GAP) activity of regulator of G protein signaling (RGS) proteins, hence involved in the termination of the signaling initiated by the G protein coupled receptors (GPCRs) by accelerating the GTP hydrolysis on the G-alpha subunits, thereby promoting their inactivation (Probable). Increases RGS9 GTPase-activating protein (GAP) activity, hence contributes to the deactivation of G protein signaling initiated by D(2) dopamine receptors (By similarity). May play an important role in neuronal signaling, incl [...]	0.481
ADGRL3	LRIT3	ENSOCUP00000030893	ENSOCUP00000003394	Adhesion G protein-coupled receptor L3; Belongs to the G-protein coupled receptor 2 family.	Leucine rich repeat, Ig-like and transmembrane domains 3.	0.770
ADGRL3	NTNG1	ENSOCUP00000030893	ENSOCUP00000025161	Adhesion G protein-coupled receptor L3; Belongs to the G-protein coupled receptor 2 family.	Netrin G1.	0.444
CACNA1F	GNB5	ENSOCUP00000004545	ENSOCUP00000010220	Calcium voltage-gated channel subunit alpha1 F.	Guanine nucleotide-binding protein subunit beta-5; Enhances GTPase-activating protein (GAP) activity of regulator of G protein signaling (RGS) proteins, hence involved in the termination of the signaling initiated by the G protein coupled receptors (GPCRs) by accelerating the GTP hydrolysis on the G-alpha subunits, thereby promoting their inactivation (Probable). Increases RGS9 GTPase-activating protein (GAP) activity, hence contributes to the deactivation of G protein signaling initiated by D(2) dopamine receptors (By similarity). May play an important role in neuronal signaling, incl [...]	0.782
CACNA1F	GRM6	ENSOCUP00000004545	ENSOCUP00000014505	Calcium voltage-gated channel subunit alpha1 F.	Metabotropic glutamate receptor 6; G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity (By similarity). Signaling stimulates TRPM1 channel activity and Ca(2+) uptake. Required for normal vision.	0.649
CACNA1F	LRIT3	ENSOCUP00000004545	ENSOCUP00000003394	Calcium voltage-gated channel subunit alpha1 F.	Leucine rich repeat, Ig-like and transmembrane domains 3.	0.891
CACNA1F	TRPM1	ENSOCUP00000004545	ENSOCUP00000041036	Calcium voltage-gated channel subunit alpha1 F.	Transient receptor potential cation channel subfamily M member 1.	0.720
GNB5	ADGRL1	ENSOCUP00000010220	ENSOCUP00000023951	Guanine nucleotide-binding protein subunit beta-5; Enhances GTPase-activating protein (GAP) activity of regulator of G protein signaling (RGS) proteins, hence involved in the termination of the signaling initiated by the G protein coupled receptors (GPCRs) by accelerating the GTP hydrolysis on the G-alpha subunits, thereby promoting their inactivation (Probable). Increases RGS9 GTPase-activating protein (GAP) activity, hence contributes to the deactivation of G protein signaling initiated by D(2) dopamine receptors (By similarity). May play an important role in neuronal signaling, incl [...]	Adhesion G protein-coupled receptor L1; Belongs to the G-protein coupled receptor 2 family.	0.481
GNB5	ADGRL2	ENSOCUP00000010220	ENSOCUP00000044036	Guanine nucleotide-binding protein subunit beta-5; Enhances GTPase-activating protein (GAP) activity of regulator of G protein signaling (RGS) proteins, hence involved in the termination of the signaling initiated by the G protein coupled receptors (GPCRs) by accelerating the GTP hydrolysis on the G-alpha subunits, thereby promoting their inactivation (Probable). Increases RGS9 GTPase-activating protein (GAP) activity, hence contributes to the deactivation of G protein signaling initiated by D(2) dopamine receptors (By similarity). May play an important role in neuronal signaling, incl [...]	Adhesion G protein-coupled receptor L2; Belongs to the G-protein coupled receptor 2 family.	0.481
GNB5	ADGRL3	ENSOCUP00000010220	ENSOCUP00000030893	Guanine nucleotide-binding protein subunit beta-5; Enhances GTPase-activating protein (GAP) activity of regulator of G protein signaling (RGS) proteins, hence involved in the termination of the signaling initiated by the G protein coupled receptors (GPCRs) by accelerating the GTP hydrolysis on the G-alpha subunits, thereby promoting their inactivation (Probable). Increases RGS9 GTPase-activating protein (GAP) activity, hence contributes to the deactivation of G protein signaling initiated by D(2) dopamine receptors (By similarity). May play an important role in neuronal signaling, incl [...]	Adhesion G protein-coupled receptor L3; Belongs to the G-protein coupled receptor 2 family.	0.481
GNB5	CACNA1F	ENSOCUP00000010220	ENSOCUP00000004545	Guanine nucleotide-binding protein subunit beta-5; Enhances GTPase-activating protein (GAP) activity of regulator of G protein signaling (RGS) proteins, hence involved in the termination of the signaling initiated by the G protein coupled receptors (GPCRs) by accelerating the GTP hydrolysis on the G-alpha subunits, thereby promoting their inactivation (Probable). Increases RGS9 GTPase-activating protein (GAP) activity, hence contributes to the deactivation of G protein signaling initiated by D(2) dopamine receptors (By similarity). May play an important role in neuronal signaling, incl [...]	Calcium voltage-gated channel subunit alpha1 F.	0.782
GNB5	GRM6	ENSOCUP00000010220	ENSOCUP00000014505	Guanine nucleotide-binding protein subunit beta-5; Enhances GTPase-activating protein (GAP) activity of regulator of G protein signaling (RGS) proteins, hence involved in the termination of the signaling initiated by the G protein coupled receptors (GPCRs) by accelerating the GTP hydrolysis on the G-alpha subunits, thereby promoting their inactivation (Probable). Increases RGS9 GTPase-activating protein (GAP) activity, hence contributes to the deactivation of G protein signaling initiated by D(2) dopamine receptors (By similarity). May play an important role in neuronal signaling, incl [...]	Metabotropic glutamate receptor 6; G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity (By similarity). Signaling stimulates TRPM1 channel activity and Ca(2+) uptake. Required for normal vision.	0.687
GNB5	LRIT3	ENSOCUP00000010220	ENSOCUP00000003394	Guanine nucleotide-binding protein subunit beta-5; Enhances GTPase-activating protein (GAP) activity of regulator of G protein signaling (RGS) proteins, hence involved in the termination of the signaling initiated by the G protein coupled receptors (GPCRs) by accelerating the GTP hydrolysis on the G-alpha subunits, thereby promoting their inactivation (Probable). Increases RGS9 GTPase-activating protein (GAP) activity, hence contributes to the deactivation of G protein signaling initiated by D(2) dopamine receptors (By similarity). May play an important role in neuronal signaling, incl [...]	Leucine rich repeat, Ig-like and transmembrane domains 3.	0.754
GNB5	RRH	ENSOCUP00000010220	ENSOCUP00000027950	Guanine nucleotide-binding protein subunit beta-5; Enhances GTPase-activating protein (GAP) activity of regulator of G protein signaling (RGS) proteins, hence involved in the termination of the signaling initiated by the G protein coupled receptors (GPCRs) by accelerating the GTP hydrolysis on the G-alpha subunits, thereby promoting their inactivation (Probable). Increases RGS9 GTPase-activating protein (GAP) activity, hence contributes to the deactivation of G protein signaling initiated by D(2) dopamine receptors (By similarity). May play an important role in neuronal signaling, incl [...]	Retinal pigment epithelium-derived rhodopsin homolog; Belongs to the G-protein coupled receptor 1 family.	0.574
GNB5	TRPM1	ENSOCUP00000010220	ENSOCUP00000041036	Guanine nucleotide-binding protein subunit beta-5; Enhances GTPase-activating protein (GAP) activity of regulator of G protein signaling (RGS) proteins, hence involved in the termination of the signaling initiated by the G protein coupled receptors (GPCRs) by accelerating the GTP hydrolysis on the G-alpha subunits, thereby promoting their inactivation (Probable). Increases RGS9 GTPase-activating protein (GAP) activity, hence contributes to the deactivation of G protein signaling initiated by D(2) dopamine receptors (By similarity). May play an important role in neuronal signaling, incl [...]	Transient receptor potential cation channel subfamily M member 1.	0.743
GRM6	CACNA1F	ENSOCUP00000014505	ENSOCUP00000004545	Metabotropic glutamate receptor 6; G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity (By similarity). Signaling stimulates TRPM1 channel activity and Ca(2+) uptake. Required for normal vision.	Calcium voltage-gated channel subunit alpha1 F.	0.649