Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KIDINS220Kinase D interacting substrate 220. (1772 aa)    
Predicted Functional Partners:
CRKL
CRK like proto-oncogene, adaptor protein.
    
 0.957
NTRK1
Tyrosine-protein kinase receptor.
    
 0.904
XPR1
Xenotropic and polytropic retrovirus receptor 1.
   
 0.870
SNX27
Sorting nexin 27.
    
 
 0.854
ENSOCUP00000027670
Ig-like domain-containing protein.
    
 0.774
NTRK2
Tyrosine-protein kinase receptor.
    
 0.722
PRKD2
Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
    
 
 0.659
PRKD1
Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
    
 
 0.653
RND2
Rho family GTPase 2.
    
 0.650
PRKD3
Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
    
 
 0.645
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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