PCNA protein (Oryctolagus cuniculus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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co-expression

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Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDK2	CDK4	ENSOCUP00000034758	ENSOCUP00000010738	Cyclin dependent kinase 2; Belongs to the protein kinase superfamily.	Cyclin dependent kinase 4; Belongs to the protein kinase superfamily.	0.983
CDK2	CDT1	ENSOCUP00000034758	ENSOCUP00000015721	Cyclin dependent kinase 2; Belongs to the protein kinase superfamily.	Chromatin licensing and DNA replication factor 1.	0.978
CDK2	FEN1	ENSOCUP00000034758	ENSOCUP00000002851	Cyclin dependent kinase 2; Belongs to the protein kinase superfamily.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.546
CDK2	LIG1	ENSOCUP00000034758	ENSOCUP00000010183	Cyclin dependent kinase 2; Belongs to the protein kinase superfamily.	DNA ligase.	0.687
CDK2	PCNA	ENSOCUP00000034758	ENSOCUP00000003512	Cyclin dependent kinase 2; Belongs to the protein kinase superfamily.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.995
CDK2	RFC4	ENSOCUP00000034758	ENSOCUP00000004340	Cyclin dependent kinase 2; Belongs to the protein kinase superfamily.	Replication factor C subunit 4.	0.485
CDK4	CDK2	ENSOCUP00000010738	ENSOCUP00000034758	Cyclin dependent kinase 4; Belongs to the protein kinase superfamily.	Cyclin dependent kinase 2; Belongs to the protein kinase superfamily.	0.983
CDK4	CDT1	ENSOCUP00000010738	ENSOCUP00000015721	Cyclin dependent kinase 4; Belongs to the protein kinase superfamily.	Chromatin licensing and DNA replication factor 1.	0.841
CDK4	FEN1	ENSOCUP00000010738	ENSOCUP00000002851	Cyclin dependent kinase 4; Belongs to the protein kinase superfamily.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.466
CDK4	LIG1	ENSOCUP00000010738	ENSOCUP00000010183	Cyclin dependent kinase 4; Belongs to the protein kinase superfamily.	DNA ligase.	0.403
CDK4	MSH6	ENSOCUP00000010738	ENSOCUP00000012569	Cyclin dependent kinase 4; Belongs to the protein kinase superfamily.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.477
CDK4	PCNA	ENSOCUP00000010738	ENSOCUP00000003512	Cyclin dependent kinase 4; Belongs to the protein kinase superfamily.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.997
CDK4	RFC4	ENSOCUP00000010738	ENSOCUP00000004340	Cyclin dependent kinase 4; Belongs to the protein kinase superfamily.	Replication factor C subunit 4.	0.454
CDT1	CDK2	ENSOCUP00000015721	ENSOCUP00000034758	Chromatin licensing and DNA replication factor 1.	Cyclin dependent kinase 2; Belongs to the protein kinase superfamily.	0.978
CDT1	CDK4	ENSOCUP00000015721	ENSOCUP00000010738	Chromatin licensing and DNA replication factor 1.	Cyclin dependent kinase 4; Belongs to the protein kinase superfamily.	0.841
CDT1	FEN1	ENSOCUP00000015721	ENSOCUP00000002851	Chromatin licensing and DNA replication factor 1.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.748
CDT1	LIG1	ENSOCUP00000015721	ENSOCUP00000010183	Chromatin licensing and DNA replication factor 1.	DNA ligase.	0.690
CDT1	MSH6	ENSOCUP00000015721	ENSOCUP00000012569	Chromatin licensing and DNA replication factor 1.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.505
CDT1	PCNA	ENSOCUP00000015721	ENSOCUP00000003512	Chromatin licensing and DNA replication factor 1.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.995
CDT1	RAD18	ENSOCUP00000015721	ENSOCUP00000029275	Chromatin licensing and DNA replication factor 1.	Uncharacterized protein.	0.411