PRSS23 protein (Oryctolagus cuniculus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

PRSS23

Serine protease 23. (387 aa)

Predicted Functional Partners:

EFEMP1

0.587

G1T067_RABIT

0.583

POSTN

0.562

TIMP3

0.557

COL6A2

0.547

TMPRSS12

0.517

PCYOX1L

0.513

FKBP10

0.503

FBN1

0.493

THBS1

0.492

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
COL6A2	EFEMP1	ENSOCUP00000000359	ENSOCUP00000012602	Uncharacterized protein.	EGF containing fibulin extracellular matrix protein 1.	0.643
COL6A2	FBN1	ENSOCUP00000000359	ENSOCUP00000003367	Uncharacterized protein.	Fibrillin 1.	0.760
COL6A2	FKBP10	ENSOCUP00000000359	ENSOCUP00000000533	Uncharacterized protein.	Peptidylprolyl isomerase.	0.649
COL6A2	POSTN	ENSOCUP00000000359	ENSOCUP00000031481	Uncharacterized protein.	Periostin.	0.729
COL6A2	PRSS23	ENSOCUP00000000359	ENSOCUP00000003578	Uncharacterized protein.	Serine protease 23.	0.547
COL6A2	THBS1	ENSOCUP00000000359	ENSOCUP00000003290	Uncharacterized protein.	Thrombospondin 1.	0.801
COL6A2	TIMP3	ENSOCUP00000000359	ENSOCUP00000007183	Uncharacterized protein.	Metalloproteinase inhibitor 3; Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. May form part of a tissue-specific acute response to remodeling stimuli (By similarity).	0.661
EFEMP1	COL6A2	ENSOCUP00000012602	ENSOCUP00000000359	EGF containing fibulin extracellular matrix protein 1.	Uncharacterized protein.	0.643
EFEMP1	FBN1	ENSOCUP00000012602	ENSOCUP00000003367	EGF containing fibulin extracellular matrix protein 1.	Fibrillin 1.	0.430
EFEMP1	FKBP10	ENSOCUP00000012602	ENSOCUP00000000533	EGF containing fibulin extracellular matrix protein 1.	Peptidylprolyl isomerase.	0.637
EFEMP1	POSTN	ENSOCUP00000012602	ENSOCUP00000031481	EGF containing fibulin extracellular matrix protein 1.	Periostin.	0.607
EFEMP1	PRSS23	ENSOCUP00000012602	ENSOCUP00000003578	EGF containing fibulin extracellular matrix protein 1.	Serine protease 23.	0.587
EFEMP1	THBS1	ENSOCUP00000012602	ENSOCUP00000003290	EGF containing fibulin extracellular matrix protein 1.	Thrombospondin 1.	0.555
EFEMP1	TIMP3	ENSOCUP00000012602	ENSOCUP00000007183	EGF containing fibulin extracellular matrix protein 1.	Metalloproteinase inhibitor 3; Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. May form part of a tissue-specific acute response to remodeling stimuli (By similarity).	0.576
FBN1	COL6A2	ENSOCUP00000003367	ENSOCUP00000000359	Fibrillin 1.	Uncharacterized protein.	0.760
FBN1	EFEMP1	ENSOCUP00000003367	ENSOCUP00000012602	Fibrillin 1.	EGF containing fibulin extracellular matrix protein 1.	0.430
FBN1	FKBP10	ENSOCUP00000003367	ENSOCUP00000000533	Fibrillin 1.	Peptidylprolyl isomerase.	0.589
FBN1	G1T067_RABIT	ENSOCUP00000003367	ENSOCUP00000009367	Fibrillin 1.	Fam20C domain-containing protein.	0.540
FBN1	POSTN	ENSOCUP00000003367	ENSOCUP00000031481	Fibrillin 1.	Periostin.	0.737
FBN1	PRSS23	ENSOCUP00000003367	ENSOCUP00000003578	Fibrillin 1.	Serine protease 23.	0.493