STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KCND2Potassium voltage-gated channel subfamily D member 2; Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes, primarily in the brain, but also in rodent heart. Mediates the major part of the dendritic A-type current I(SA) in brain neurons (By similarity). This current is activated at membrane potentials that are below the threshold for action potentials. It regulates neuronal excitability, prolongs the latency before the first spike in a series of action potentials, regulates the frequency of repetitive action potential firing, shortens t [...] (630 aa)    
Predicted Functional Partners:
KCNN2
Potassium calcium-activated channel subfamily N member 2.
   
 
 0.937
KCNIP1
Potassium voltage-gated channel interacting protein 1.
   
 0.926
KCNIP2
Potassium voltage-gated channel interacting protein 2.
    
 0.902
DPP6
Dipeptidyl peptidase like 6; Belongs to the peptidase S9B family.
    
 
 0.902
G1U1Y5_RABIT
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
   
 0.809
FAU
Ubiquitin-like domain-containing protein.
   
 0.809
ENSOCUP00000046875
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
   
 0.809
ENSOCUP00000049185
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
   
 0.809
KCNIP4
Potassium voltage-gated channel interacting protein 4.
   
 0.808
DPP10
Dipeptidyl peptidase like 10; Belongs to the peptidase S9B family.
    
 
 0.744
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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