Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MYH9Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1920 aa)    
Predicted Functional Partners:
MYH10
Myosin heavy chain 10; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
  
0.999
MYH11
Myosin-11; Muscle contraction.
  
0.998
MYL9
Myosin light chain 9.
   
 0.997
ENSOCUP00000031289
Uncharacterized protein.
   
 0.997
LOC100349824
Uncharacterized protein.
   
 0.988
MYL12A
Myosin light chain 12A.
   
 0.980
ENSOCUP00000030344
EF-hand domain-containing protein.
   
 0.950
S100A4
Protein S100; Belongs to the S-100 family.
    
 0.939
ACTG2
Actin gamma 2, smooth muscle.
   
 0.934
MYL2
Myosin regulatory light chain 2, ventricular/cardiac muscle isoform; Contractile protein that plays a role in heart development and function (By similarity). Following phosphorylation, plays a role in cross-bridge cycling kinetics and cardiac muscle contraction by increasing myosin lever arm stiffness and promoting myosin head diffusion; as a consequence of the increase in maximum contraction force and calcium sensitivity of contraction force. These events altogether slow down myosin kinetics and prolong duty cycle resulting in accumulated myosins being cooperatively recruited to actin [...]
   
 0.932
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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