ICE2 protein (Oryctolagus cuniculus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ICE2

Interactor of little elongation complex ELL subunit 2. (965 aa)

Predicted Functional Partners:

ELL3

0.912

ZC3H8

0.888

ELL2

0.877

USPL1

0.782

MED26

0.755

LOC100352616

0.752

RPAP2

0.728

FNDC7

0.698

ICE1

0.695

EAF1

0.689

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EAF1	ELL2	ENSOCUP00000013830	ENSOCUP00000006190	ELL associated factor 1.	Elongation factor for RNA polymerase II 2.	0.939
EAF1	ELL3	ENSOCUP00000013830	ENSOCUP00000001007	ELL associated factor 1.	Uncharacterized protein.	0.916
EAF1	ICE2	ENSOCUP00000013830	ENSOCUP00000003593	ELL associated factor 1.	Interactor of little elongation complex ELL subunit 2.	0.689
EAF1	LOC100352616	ENSOCUP00000013830	ENSOCUP00000016910	ELL associated factor 1.	Uncharacterized protein.	0.939
EAF1	MED26	ENSOCUP00000013830	ENSOCUP00000034616	ELL associated factor 1.	TFS2N domain-containing protein.	0.764
ELL2	EAF1	ENSOCUP00000006190	ENSOCUP00000013830	Elongation factor for RNA polymerase II 2.	ELL associated factor 1.	0.939
ELL2	ELL3	ENSOCUP00000006190	ENSOCUP00000001007	Elongation factor for RNA polymerase II 2.	Uncharacterized protein.	0.699
ELL2	ICE1	ENSOCUP00000006190	ENSOCUP00000025130	Elongation factor for RNA polymerase II 2.	Interactor of little elongation complex ELL subunit 1.	0.444
ELL2	ICE2	ENSOCUP00000006190	ENSOCUP00000003593	Elongation factor for RNA polymerase II 2.	Interactor of little elongation complex ELL subunit 2.	0.877
ELL2	MED26	ENSOCUP00000006190	ENSOCUP00000034616	Elongation factor for RNA polymerase II 2.	TFS2N domain-containing protein.	0.841
ELL2	RPAP2	ENSOCUP00000006190	ENSOCUP00000001552	Elongation factor for RNA polymerase II 2.	RNA polymerase II associated protein 2.	0.462
ELL2	USPL1	ENSOCUP00000006190	ENSOCUP00000009592	Elongation factor for RNA polymerase II 2.	Ubiquitin specific peptidase like 1.	0.418
ELL2	ZC3H8	ENSOCUP00000006190	ENSOCUP00000028419	Elongation factor for RNA polymerase II 2.	Zinc finger CCCH-type containing 8.	0.561
ELL3	EAF1	ENSOCUP00000001007	ENSOCUP00000013830	Uncharacterized protein.	ELL associated factor 1.	0.916
ELL3	ELL2	ENSOCUP00000001007	ENSOCUP00000006190	Uncharacterized protein.	Elongation factor for RNA polymerase II 2.	0.699
ELL3	ICE1	ENSOCUP00000001007	ENSOCUP00000025130	Uncharacterized protein.	Interactor of little elongation complex ELL subunit 1.	0.444
ELL3	ICE2	ENSOCUP00000001007	ENSOCUP00000003593	Uncharacterized protein.	Interactor of little elongation complex ELL subunit 2.	0.912
ELL3	LOC100352616	ENSOCUP00000001007	ENSOCUP00000016910	Uncharacterized protein.	Uncharacterized protein.	0.603
ELL3	MED26	ENSOCUP00000001007	ENSOCUP00000034616	Uncharacterized protein.	TFS2N domain-containing protein.	0.860
ELL3	RPAP2	ENSOCUP00000001007	ENSOCUP00000001552	Uncharacterized protein.	RNA polymerase II associated protein 2.	0.462