STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VSIG4V-set and immunoglobulin domain containing 4. (411 aa)    
Predicted Functional Partners:
MS4A4A
Uncharacterized protein.
   
  
 0.891
C1QA
Complement C1q A chain.
   
  
 0.879
C1QC
Complement C1q C chain.
   
  
 0.825
CD163
CD163 molecule.
   
  
 0.785
C3
Complement C3 alpha chain; C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates.
    
 
 0.749
LOC100346672
Uncharacterized protein.
    
 
 0.749
CD207
CD207 molecule.
   
  
 0.648
C4A
Uncharacterized protein.
    
 
 0.612
CSF1R
Colony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
   
  
 0.609
IRF5
Interferon regulatory factor 5.
   
  
 0.548
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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