Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IKIK cytokine. (557 aa)    
Predicted Functional Partners:
SMU1
SMU1 DNA replication regulator and spliceosomal factor.
   
 0.993
PRPF6
Pre-mRNA processing factor 6.
   
 0.980
MFAP1
Microfibrillar-associated protein 1 (Predicted).
   
 0.952
ZMAT2
Zinc finger matrin-type 2.
   
  0.932
WBP4
WW domain binding protein 4.
    
  0.927
PRPF38A
Pre-mRNA processing factor 38A.
   
 
 0.920
PRPF3
Pre-mRNA processing factor 3.
   
  0.913
TCERG1
Transcription elongation regulator 1.
   
  0.903
WBP11
Uncharacterized protein.
   
  0.899
WDR55
WD repeat-containing protein 55; Nucleolar protein that acts as a modulator of rRNA synthesis. Plays a central role during organogenesis. Belongs to the WD repeat WDR55 family.
 
      0.899
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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