Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SEMA5ASemaphorin 5A. (978 aa)    
Predicted Functional Partners:
PLXNB3
Plexin B3.
    
 0.943
PLXNB1
Plexin B1.
    
 0.836
PLXND1
Plexin D1.
    
 0.729
PLXNA2
Plexin A2.
    
 0.728
PLXNA3
Sema domain-containing protein.
    
 0.727
PLXNA1
Plexin A1.
    
 0.719
PLXNC1
Plexin_cytopl domain-containing protein.
    
 0.653
NRP1
Neuropilin; Belongs to the neuropilin family.
    
 0.651
PLXNA4
Plexin A4.
    
0.594
SDK2
Sidekick cell adhesion molecule 2.
   
 
 0.563
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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