STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SLF1SMC5-SMC6 complex localization factor 1. (1015 aa)    
Predicted Functional Partners:
ATR
ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.
   
 0.993
BARD1
BRCA1 associated RING domain 1.
   
0.992
BRIP1
BRCA1 interacting protein C-terminal helicase 1.
   
 0.991
PSMD12
Proteasome 26S subunit, non-ATPase 12.
    
 0.988
NBN
Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis.
   
 0.985
WRN
WRN RecQ like helicase.
   
 0.981
RAD17
RAD17 checkpoint clamp loader component.
   
 0.979
RHNO1
RAD9-HUS1-RAD1 interacting nuclear orphan 1.
  
 
 0.976
RAD1
RAD1 checkpoint DNA exonuclease.
   
 0.976
RFC4
Replication factor C subunit 4.
   
 0.971
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.