STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FYCO1FYVE and coiled-coil domain containing 1. (1470 aa)    
Predicted Functional Partners:
RAB7A
Ras-related protein Rab-7a; Key regulator in endo-lysosomal trafficking. Governs early- to-late endosomal maturation, microtubule minus-end as well as plus-end directed endosomal migration and positioning, and endosome-lysosome transport through different protein-protein interaction cascades (By similarity). Plays a central role, not only in endosomal traffic, but also in many other cellular and physiological events, such as growth- factor-mediated cell signaling, nutrient-transportor mediated nutrient uptake, neurotrophin transport in the axons of neurons and lipid metabolism (By simi [...]
    
 0.953
RAB7B
Uncharacterized protein.
     
 0.911
MAP1LC3B
Uncharacterized protein.
   
 
 0.784
ZFYVE27
Zinc finger FYVE-type containing 27.
   
  
 0.778
ENSOCUP00000033272
Uncharacterized protein.
   
 
 0.755
ENSOCUP00000033398
Uncharacterized protein.
   
 
 0.755
LZTFL1
Leucine zipper transcription factor like 1.
 
    
 0.738
ARL8B
Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.
    
 0.716
PLEKHM1
Pleckstrin homology and RUN domain containing M1.
    
 
 0.711
NBR1
NBR1 autophagy cargo receptor.
   
  
 0.709
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.