Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EMC3ER membrane protein complex subunit 3; Belongs to the EMC3 family. (284 aa)    
Predicted Functional Partners:
EMC4
ER membrane protein complex subunit 4; Belongs to the EMC4 family.
   
 0.991
EMC1
ER membrane protein complex subunit 1.
   
 0.988
EMC2
ER membrane protein complex subunit 2.
   
 0.987
EMC7
ER membrane protein complex subunit 7.
   
 0.985
EMC9
ER membrane protein complex subunit 9.
   
 0.983
MMGT1
Uncharacterized protein.
   
 0.919
ENSOCUP00000034905
Uncharacterized protein.
   
 0.903
TMCO1
Transmembrane and coiled-coil domains 1.
   
 
 0.856
LMAN1
Lectin, mannose binding 1.
   
 
 0.829
DERL2
Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.
   
 
 0.776
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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