PARP6 protein (Oryctolagus cuniculus) - STRING interaction network

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Score

PARP6

Poly [ADP-ribose] polymerase. (630 aa)

Predicted Functional Partners:

AK9

0.861

GPI

0.856

H6PD

0.831

PARP4

0.808

ENO4

0.783

PARP14

0.754

PARP12

0.749

TPI1

0.729

PARP3

0.708

ENO2

0.697

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AK9	H6PD	ENSOCUP00000005312	ENSOCUP00000000694	Uncharacterized protein.	GDH/6PGL endoplasmic bifunctional protein; Bifunctional enzyme localized in the lumen of the endoplasmic reticulum that catalyzes the first two steps of the oxidative branch of the pentose phosphate pathway/shunt, an alternative to glycolysis and a major source of reducing power and metabolic intermediates for biosynthetic processes. Has a hexose-6-phosphate dehydrogenase activity, with broad substrate specificity compared to glucose-6- phosphate 1-dehydrogenase/G6PD, and catalyzes the first step of the pentose phosphate pathway. In addition, acts as a 6- phosphogluconolactonase and ca [...]	0.467
AK9	PARP6	ENSOCUP00000005312	ENSOCUP00000003779	Uncharacterized protein.	Poly [ADP-ribose] polymerase.	0.861
AK9	TPI1	ENSOCUP00000005312	ENSOCUP00000019840	Uncharacterized protein.	Triosephosphate isomerase; Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis.	0.413
ENO2	ENO4	ENSOCUP00000003109	ENSOCUP00000034039	Beta-enolase; Appears to have a function in striated muscle development and regeneration; Belongs to the enolase family.	Enolase 4.	0.880
ENO2	GPI	ENSOCUP00000003109	ENSOCUP00000036902	Beta-enolase; Appears to have a function in striated muscle development and regeneration; Belongs to the enolase family.	Glucose-6-phosphate isomerase; In the cytoplasm, catalyzes the conversion of glucose-6- phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis (By similarity). Besides it's role as a glycolytic enzyme, also acts as a secreted cytokine: acts as an angiogenic factor (AMF) that stimulates endothelial cell motility. Acts as a neurotrophic factor, neuroleukin, for spinal and sensory neurons. It is secreted by lectin-stimulated T-cells and induces immunoglobulin secretion (By similarity).	0.950
ENO2	H6PD	ENSOCUP00000003109	ENSOCUP00000000694	Beta-enolase; Appears to have a function in striated muscle development and regeneration; Belongs to the enolase family.	GDH/6PGL endoplasmic bifunctional protein; Bifunctional enzyme localized in the lumen of the endoplasmic reticulum that catalyzes the first two steps of the oxidative branch of the pentose phosphate pathway/shunt, an alternative to glycolysis and a major source of reducing power and metabolic intermediates for biosynthetic processes. Has a hexose-6-phosphate dehydrogenase activity, with broad substrate specificity compared to glucose-6- phosphate 1-dehydrogenase/G6PD, and catalyzes the first step of the pentose phosphate pathway. In addition, acts as a 6- phosphogluconolactonase and ca [...]	0.829
ENO2	PARP6	ENSOCUP00000003109	ENSOCUP00000003779	Beta-enolase; Appears to have a function in striated muscle development and regeneration; Belongs to the enolase family.	Poly [ADP-ribose] polymerase.	0.697
ENO2	TPI1	ENSOCUP00000003109	ENSOCUP00000019840	Beta-enolase; Appears to have a function in striated muscle development and regeneration; Belongs to the enolase family.	Triosephosphate isomerase; Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis.	0.977
ENO4	ENO2	ENSOCUP00000034039	ENSOCUP00000003109	Enolase 4.	Beta-enolase; Appears to have a function in striated muscle development and regeneration; Belongs to the enolase family.	0.880
ENO4	GPI	ENSOCUP00000034039	ENSOCUP00000036902	Enolase 4.	Glucose-6-phosphate isomerase; In the cytoplasm, catalyzes the conversion of glucose-6- phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis (By similarity). Besides it's role as a glycolytic enzyme, also acts as a secreted cytokine: acts as an angiogenic factor (AMF) that stimulates endothelial cell motility. Acts as a neurotrophic factor, neuroleukin, for spinal and sensory neurons. It is secreted by lectin-stimulated T-cells and induces immunoglobulin secretion (By similarity).	0.969
ENO4	H6PD	ENSOCUP00000034039	ENSOCUP00000000694	Enolase 4.	GDH/6PGL endoplasmic bifunctional protein; Bifunctional enzyme localized in the lumen of the endoplasmic reticulum that catalyzes the first two steps of the oxidative branch of the pentose phosphate pathway/shunt, an alternative to glycolysis and a major source of reducing power and metabolic intermediates for biosynthetic processes. Has a hexose-6-phosphate dehydrogenase activity, with broad substrate specificity compared to glucose-6- phosphate 1-dehydrogenase/G6PD, and catalyzes the first step of the pentose phosphate pathway. In addition, acts as a 6- phosphogluconolactonase and ca [...]	0.892
ENO4	PARP6	ENSOCUP00000034039	ENSOCUP00000003779	Enolase 4.	Poly [ADP-ribose] polymerase.	0.783
ENO4	TPI1	ENSOCUP00000034039	ENSOCUP00000019840	Enolase 4.	Triosephosphate isomerase; Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis.	0.920
GPI	ENO2	ENSOCUP00000036902	ENSOCUP00000003109	Glucose-6-phosphate isomerase; In the cytoplasm, catalyzes the conversion of glucose-6- phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis (By similarity). Besides it's role as a glycolytic enzyme, also acts as a secreted cytokine: acts as an angiogenic factor (AMF) that stimulates endothelial cell motility. Acts as a neurotrophic factor, neuroleukin, for spinal and sensory neurons. It is secreted by lectin-stimulated T-cells and induces immunoglobulin secretion (By similarity).	Beta-enolase; Appears to have a function in striated muscle development and regeneration; Belongs to the enolase family.	0.950
GPI	ENO4	ENSOCUP00000036902	ENSOCUP00000034039	Glucose-6-phosphate isomerase; In the cytoplasm, catalyzes the conversion of glucose-6- phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis (By similarity). Besides it's role as a glycolytic enzyme, also acts as a secreted cytokine: acts as an angiogenic factor (AMF) that stimulates endothelial cell motility. Acts as a neurotrophic factor, neuroleukin, for spinal and sensory neurons. It is secreted by lectin-stimulated T-cells and induces immunoglobulin secretion (By similarity).	Enolase 4.	0.969
GPI	H6PD	ENSOCUP00000036902	ENSOCUP00000000694	Glucose-6-phosphate isomerase; In the cytoplasm, catalyzes the conversion of glucose-6- phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis (By similarity). Besides it's role as a glycolytic enzyme, also acts as a secreted cytokine: acts as an angiogenic factor (AMF) that stimulates endothelial cell motility. Acts as a neurotrophic factor, neuroleukin, for spinal and sensory neurons. It is secreted by lectin-stimulated T-cells and induces immunoglobulin secretion (By similarity).	GDH/6PGL endoplasmic bifunctional protein; Bifunctional enzyme localized in the lumen of the endoplasmic reticulum that catalyzes the first two steps of the oxidative branch of the pentose phosphate pathway/shunt, an alternative to glycolysis and a major source of reducing power and metabolic intermediates for biosynthetic processes. Has a hexose-6-phosphate dehydrogenase activity, with broad substrate specificity compared to glucose-6- phosphate 1-dehydrogenase/G6PD, and catalyzes the first step of the pentose phosphate pathway. In addition, acts as a 6- phosphogluconolactonase and ca [...]	0.986
GPI	PARP6	ENSOCUP00000036902	ENSOCUP00000003779	Glucose-6-phosphate isomerase; In the cytoplasm, catalyzes the conversion of glucose-6- phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis (By similarity). Besides it's role as a glycolytic enzyme, also acts as a secreted cytokine: acts as an angiogenic factor (AMF) that stimulates endothelial cell motility. Acts as a neurotrophic factor, neuroleukin, for spinal and sensory neurons. It is secreted by lectin-stimulated T-cells and induces immunoglobulin secretion (By similarity).	Poly [ADP-ribose] polymerase.	0.856
GPI	TPI1	ENSOCUP00000036902	ENSOCUP00000019840	Glucose-6-phosphate isomerase; In the cytoplasm, catalyzes the conversion of glucose-6- phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis (By similarity). Besides it's role as a glycolytic enzyme, also acts as a secreted cytokine: acts as an angiogenic factor (AMF) that stimulates endothelial cell motility. Acts as a neurotrophic factor, neuroleukin, for spinal and sensory neurons. It is secreted by lectin-stimulated T-cells and induces immunoglobulin secretion (By similarity).	Triosephosphate isomerase; Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis.	0.998
H6PD	AK9	ENSOCUP00000000694	ENSOCUP00000005312	GDH/6PGL endoplasmic bifunctional protein; Bifunctional enzyme localized in the lumen of the endoplasmic reticulum that catalyzes the first two steps of the oxidative branch of the pentose phosphate pathway/shunt, an alternative to glycolysis and a major source of reducing power and metabolic intermediates for biosynthetic processes. Has a hexose-6-phosphate dehydrogenase activity, with broad substrate specificity compared to glucose-6- phosphate 1-dehydrogenase/G6PD, and catalyzes the first step of the pentose phosphate pathway. In addition, acts as a 6- phosphogluconolactonase and ca [...]	Uncharacterized protein.	0.467
H6PD	ENO2	ENSOCUP00000000694	ENSOCUP00000003109	GDH/6PGL endoplasmic bifunctional protein; Bifunctional enzyme localized in the lumen of the endoplasmic reticulum that catalyzes the first two steps of the oxidative branch of the pentose phosphate pathway/shunt, an alternative to glycolysis and a major source of reducing power and metabolic intermediates for biosynthetic processes. Has a hexose-6-phosphate dehydrogenase activity, with broad substrate specificity compared to glucose-6- phosphate 1-dehydrogenase/G6PD, and catalyzes the first step of the pentose phosphate pathway. In addition, acts as a 6- phosphogluconolactonase and ca [...]	Beta-enolase; Appears to have a function in striated muscle development and regeneration; Belongs to the enolase family.	0.829