STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PARP6Poly [ADP-ribose] polymerase. (630 aa)    
Predicted Functional Partners:
PARP4
Poly [ADP-ribose] polymerase.
      
 0.844
RPS15
Ribosomal protein S15; Belongs to the universal ribosomal protein uS19 family.
  
 0.812
GPI
Glucose-6-phosphate isomerase; In the cytoplasm, catalyzes the conversion of glucose-6- phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis (By similarity). Besides it's role as a glycolytic enzyme, also acts as a secreted cytokine: acts as an angiogenic factor (AMF) that stimulates endothelial cell motility. Acts as a neurotrophic factor, neuroleukin, for spinal and sensory neurons. It is secreted by lectin-stimulated T-cells and induces immunoglobulin secretion (By similarity).
  
 
 0.771
PARP14
Poly [ADP-ribose] polymerase.
   
  
 0.759
IMP3
S4 RNA-binding domain-containing protein.
  
 
 0.747
PARP12
Poly(ADP-ribose) polymerase family member 12.
   
  
 0.730
RPL23
Uncharacterized protein; Belongs to the universal ribosomal protein uL14 family.
  
   0.724
LOC100341783
Uncharacterized protein; Belongs to the universal ribosomal protein uL14 family.
  
   0.724
CUL7
Cullin 7; Belongs to the cullin family.
  
 
 0.723
TPI1
Triosephosphate isomerase; Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis.
  
  
 0.723
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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