ARRDC3 protein (Oryctolagus cuniculus) - STRING interaction network

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Score

ARRDC3

Arrestin domain containing 3. (414 aa)

Predicted Functional Partners:

NEDD4

0.952

ADRB2

0.716

WWP2

0.706

FAM228B

0.679

AQP10

0.648

NEDD4L

0.628

ITGAL

0.595

KLHDC8B

0.592

PLEKHA5

0.580

ARRB1

0.571

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADRB2	ARRB1	ENSOCUP00000013826	ENSOCUP00000019641	Adrenoceptor beta 2.	Beta-arrestin-1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...]	0.843
ADRB2	ARRDC3	ENSOCUP00000013826	ENSOCUP00000003780	Adrenoceptor beta 2.	Arrestin domain containing 3.	0.716
AQP10	ARRDC3	ENSOCUP00000026106	ENSOCUP00000003780	Aquaporin 10; Belongs to the MIP/aquaporin (TC 1.A.8) family.	Arrestin domain containing 3.	0.648
ARRB1	ADRB2	ENSOCUP00000019641	ENSOCUP00000013826	Beta-arrestin-1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...]	Adrenoceptor beta 2.	0.843
ARRB1	ARRDC3	ENSOCUP00000019641	ENSOCUP00000003780	Beta-arrestin-1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...]	Arrestin domain containing 3.	0.571
ARRB1	NEDD4	ENSOCUP00000019641	ENSOCUP00000005929	Beta-arrestin-1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...]	NEDD4 E3 ubiquitin protein ligase.	0.522
ARRDC3	ADRB2	ENSOCUP00000003780	ENSOCUP00000013826	Arrestin domain containing 3.	Adrenoceptor beta 2.	0.716
ARRDC3	AQP10	ENSOCUP00000003780	ENSOCUP00000026106	Arrestin domain containing 3.	Aquaporin 10; Belongs to the MIP/aquaporin (TC 1.A.8) family.	0.648
ARRDC3	ARRB1	ENSOCUP00000003780	ENSOCUP00000019641	Arrestin domain containing 3.	Beta-arrestin-1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...]	0.571
ARRDC3	FAM228B	ENSOCUP00000003780	ENSOCUP00000034734	Arrestin domain containing 3.	Uncharacterized protein.	0.679
ARRDC3	ITGAL	ENSOCUP00000003780	ENSOCUP00000012355	Arrestin domain containing 3.	Integrin subunit alpha L; Belongs to the integrin alpha chain family.	0.595
ARRDC3	KLHDC8B	ENSOCUP00000003780	ENSOCUP00000015105	Arrestin domain containing 3.	Kelch domain containing 8B.	0.592
ARRDC3	NEDD4	ENSOCUP00000003780	ENSOCUP00000005929	Arrestin domain containing 3.	NEDD4 E3 ubiquitin protein ligase.	0.952
ARRDC3	NEDD4L	ENSOCUP00000003780	ENSOCUP00000039298	Arrestin domain containing 3.	NEDD4 like E3 ubiquitin protein ligase.	0.628
ARRDC3	PLEKHA5	ENSOCUP00000003780	ENSOCUP00000023931	Arrestin domain containing 3.	Pleckstrin homology domain containing A5.	0.580
ARRDC3	WWP2	ENSOCUP00000003780	ENSOCUP00000009267	Arrestin domain containing 3.	E3 ubiquitin-protein ligase.	0.706
FAM228B	ARRDC3	ENSOCUP00000034734	ENSOCUP00000003780	Uncharacterized protein.	Arrestin domain containing 3.	0.679
ITGAL	ARRDC3	ENSOCUP00000012355	ENSOCUP00000003780	Integrin subunit alpha L; Belongs to the integrin alpha chain family.	Arrestin domain containing 3.	0.595
KLHDC8B	ARRDC3	ENSOCUP00000015105	ENSOCUP00000003780	Kelch domain containing 8B.	Arrestin domain containing 3.	0.592
NEDD4	ARRB1	ENSOCUP00000005929	ENSOCUP00000019641	NEDD4 E3 ubiquitin protein ligase.	Beta-arrestin-1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...]	0.522