ARRDC3 protein (Oryctolagus cuniculus) - STRING interaction network

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Score

ARRDC3

Arrestin domain containing 3. (414 aa)

Predicted Functional Partners:

NEDD4

0.958

ADRB2

0.929

ITCH

0.924

WWP2

0.910

NEDD4L

0.831

WWP1

0.821

CUEDC1

0.758

ARRB1

0.688

TOM1

0.631

F2R

0.607

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADRB2	ARRB1	ENSOCUP00000013826	ENSOCUP00000019641	Adrenoceptor beta 2.	Beta-arrestin-1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...]	0.943
ADRB2	ARRDC3	ENSOCUP00000013826	ENSOCUP00000003780	Adrenoceptor beta 2.	Arrestin domain containing 3.	0.929
ADRB2	NEDD4	ENSOCUP00000013826	ENSOCUP00000005929	Adrenoceptor beta 2.	NEDD4 E3 ubiquitin protein ligase.	0.676
ADRB2	NEDD4L	ENSOCUP00000013826	ENSOCUP00000039298	Adrenoceptor beta 2.	NEDD4 like E3 ubiquitin protein ligase.	0.408
ARRB1	ADRB2	ENSOCUP00000019641	ENSOCUP00000013826	Beta-arrestin-1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...]	Adrenoceptor beta 2.	0.943
ARRB1	ARRDC3	ENSOCUP00000019641	ENSOCUP00000003780	Beta-arrestin-1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...]	Arrestin domain containing 3.	0.688
ARRB1	F2R	ENSOCUP00000019641	ENSOCUP00000020419	Beta-arrestin-1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...]	Coagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family.	0.847
ARRB1	ITCH	ENSOCUP00000019641	ENSOCUP00000013200	Beta-arrestin-1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...]	E3 ubiquitin-protein ligase.	0.584
ARRB1	NEDD4	ENSOCUP00000019641	ENSOCUP00000005929	Beta-arrestin-1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...]	NEDD4 E3 ubiquitin protein ligase.	0.554
ARRDC3	ADRB2	ENSOCUP00000003780	ENSOCUP00000013826	Arrestin domain containing 3.	Adrenoceptor beta 2.	0.929
ARRDC3	ARRB1	ENSOCUP00000003780	ENSOCUP00000019641	Arrestin domain containing 3.	Beta-arrestin-1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...]	0.688
ARRDC3	CUEDC1	ENSOCUP00000003780	ENSOCUP00000029312	Arrestin domain containing 3.	CUE domain containing 1.	0.758
ARRDC3	F2R	ENSOCUP00000003780	ENSOCUP00000020419	Arrestin domain containing 3.	Coagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family.	0.607
ARRDC3	ITCH	ENSOCUP00000003780	ENSOCUP00000013200	Arrestin domain containing 3.	E3 ubiquitin-protein ligase.	0.924
ARRDC3	NEDD4	ENSOCUP00000003780	ENSOCUP00000005929	Arrestin domain containing 3.	NEDD4 E3 ubiquitin protein ligase.	0.958
ARRDC3	NEDD4L	ENSOCUP00000003780	ENSOCUP00000039298	Arrestin domain containing 3.	NEDD4 like E3 ubiquitin protein ligase.	0.831
ARRDC3	TOM1	ENSOCUP00000003780	ENSOCUP00000026311	Arrestin domain containing 3.	Target of myb1 membrane trafficking protein; Belongs to the TOM1 family.	0.631
ARRDC3	WWP1	ENSOCUP00000003780	ENSOCUP00000000938	Arrestin domain containing 3.	E3 ubiquitin-protein ligase.	0.821
ARRDC3	WWP2	ENSOCUP00000003780	ENSOCUP00000009267	Arrestin domain containing 3.	E3 ubiquitin-protein ligase.	0.910
CUEDC1	ARRDC3	ENSOCUP00000029312	ENSOCUP00000003780	CUE domain containing 1.	Arrestin domain containing 3.	0.758