STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CREB3L1cAMP responsive element binding protein 3 like 1. (477 aa)    
Predicted Functional Partners:
SEC24D
SEC24 homolog D, COPII coat complex component.
   
  
 0.742
TM4SF20
Transmembrane 4 L six family member 20.
      
 0.679
MBTPS2
Membrane bound transcription factor peptidase, site 2.
     
 0.657
ATF6
Activating transcription factor 6.
    
 
 0.620
C11orf49
Chromosome 11 open reading frame 49.
      
 0.609
MBTPS1
Membrane bound transcription factor peptidase, site 1.
   
 
 0.563
PTGS2
Prostaglandin G/H synthase 2; Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and in pathological conditions, such as in cancer. PTGS2 is responsible for production of inflammatory prostaglandins. Up-regulation of PTGS2 is also associated with increased cell adhesion, phenotypic changes, resistance to apoptosis and tumor angiogenesis. In cancer cells, PTGS2 is a key step in the production of prostaglandin E2 (PGE2), which plays imp [...]
      
 0.530
SEC24C
Uncharacterized protein.
   
  
 0.523
KDELR3
ER lumen protein-retaining receptor.
   
  
 0.491
WIF1
WNT inhibitory factor 1.
   
  
 0.470
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.