Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
HNRNPH3Heterogeneous nuclear ribonucleoprotein H3. (346 aa)    
Predicted Functional Partners:
HNRNPD
Heterogeneous nuclear ribonucleoprotein D.
   
 0.881
HNRNPDL
Heterogeneous nuclear ribonucleoprotein D like.
   
 0.880
HNRNPA2B1-2
Heterogeneous nuclear ribonucleoprotein A2/B1.
   
 0.877
HNRNPA2B1
Heterogeneous nuclear ribonucleoprotein A2/B1.
   
 0.876
HNRNPUL1
Heterogeneous nuclear ribonucleoprotein U like 1.
   
 0.844
G1U371_RABIT
Uncharacterized protein.
   
 0.829
ENSOCUP00000031127
Uncharacterized protein.
   
  0.814
HNRNPAB
Heterogeneous nuclear ribonucleoprotein A/B.
   
 0.814
HNRNPU
Heterogeneous nuclear ribonucleoprotein U.
   
 0.813
HNRNPK
Heterogeneous nuclear ribonucleoprotein K; One of the major pre-mRNA-binding proteins. Binds tenaciously to poly(C) sequences. Likely to play a role in the nuclear metabolism of hnRNAs, particularly for pre-mRNAs that contain cytidine-rich sequences. Can also bind poly(C) single-stranded DNA. Plays an important role in p53/TP53 response to DNA damage, acting at the level of both transcription activation and repression. When sumoylated, acts as a transcriptional coactivator of p53/TP53, playing a role in p21/CDKN1A and 14-3-3 sigma/SFN induction. As far as transcription repression is co [...]
   
 0.811
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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