STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ALPLAlkaline phosphatase. (558 aa)    
Predicted Functional Partners:
BGLAP
Osteocalcin; Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium.
      
 0.858
RUNX2
RUNX family transcription factor 2.
      
 0.852
IBSP
Integrin binding sialoprotein.
   
  
 0.813
COL1A1
Collagen alpha-1(I) chain.
   
  
 0.788
SP7
Sp7 transcription factor.
   
  
 0.782
COL10A1
C1q domain-containing protein.
   
  
 0.753
COL2A1
Fibrillar collagen NC1 domain-containing protein.
   
  
 0.727
SOST
Sclerostin.
   
  
 0.719
SPP1
Osteopontin; Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction; Belongs to the osteopontin family.
   
  
 0.704
PHEX
Phosphate regulating endopeptidase homolog X-linked.
   
  
 0.693
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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