Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SERPINB13SERPIN domain-containing protein; Belongs to the serpin family. (404 aa)    
Predicted Functional Partners:
CTSV
Cathepsin V; Belongs to the peptidase C1 family.
   
 0.893
CTSG
Cathepsin G.
   
 0.891
CTSK
Cathepsin K; Thiol protease involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degradation. Involved in the release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen. Belongs to the peptidase C1 family.
    
 0.853
SERPINB10
SERPIN domain-containing protein; Belongs to the serpin family.
     
  0.732
ZNF250
Zinc finger protein 250.
    
 
 0.691
SERPINB6
SERPIN domain-containing protein; Belongs to the serpin family.
     
  0.689
KAT14
Lysine acetyltransferase 14.
    
 
 0.676
CTSS
Cathepsin S; Belongs to the peptidase C1 family.
    
 0.652
LCP1
Lymphocyte cytosolic protein 1.
    
 
 0.634
SERPING1
Plasma protease C1 inhibitor; Belongs to the serpin family.
  
  0.633
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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