ANKRD6 protein (Oryctolagus cuniculus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ANKRD6

Ankyrin repeat domain 6. (717 aa)

Predicted Functional Partners:

APP

0.686

ENSOCUP00000036387

0.678

PRICKLE2

0.666

REL

0.661

ENSOCUP00000046340

0.661

PRICKLE1

0.657

TNIP2

0.641

VANGL1

0.614

IKBKB

0.601

CHUK

0.601

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANKRD6	APP	ENSOCUP00000003910	ENSOCUP00000009130	Ankyrin repeat domain 6.	Gamma-secretase C-terminal fragment 57; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...]	0.686
ANKRD6	CHUK	ENSOCUP00000003910	ENSOCUP00000031319	Ankyrin repeat domain 6.	Component of inhibitor of nuclear factor kappa B kinase complex.	0.601
ANKRD6	ENSOCUP00000036387	ENSOCUP00000003910	ENSOCUP00000036387	Ankyrin repeat domain 6.	DIX domain-containing protein.	0.678
ANKRD6	ENSOCUP00000046340	ENSOCUP00000003910	ENSOCUP00000046340	Ankyrin repeat domain 6.	RHD domain-containing protein.	0.661
ANKRD6	IKBKB	ENSOCUP00000003910	ENSOCUP00000006175	Ankyrin repeat domain 6.	Inhibitor of nuclear factor kappa B kinase subunit beta.	0.601
ANKRD6	PRICKLE1	ENSOCUP00000003910	ENSOCUP00000046353	Ankyrin repeat domain 6.	Prickle planar cell polarity protein 1.	0.657
ANKRD6	PRICKLE2	ENSOCUP00000003910	ENSOCUP00000000705	Ankyrin repeat domain 6.	Prickle planar cell polarity protein 2.	0.666
ANKRD6	REL	ENSOCUP00000003910	ENSOCUP00000004298	Ankyrin repeat domain 6.	REL proto-oncogene, NF-kB subunit.	0.661
ANKRD6	TNIP2	ENSOCUP00000003910	ENSOCUP00000008641	Ankyrin repeat domain 6.	TNFAIP3 interacting protein 2.	0.641
ANKRD6	VANGL1	ENSOCUP00000003910	ENSOCUP00000022295	Ankyrin repeat domain 6.	Vang-like protein.	0.614
APP	ANKRD6	ENSOCUP00000009130	ENSOCUP00000003910	Gamma-secretase C-terminal fragment 57; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...]	Ankyrin repeat domain 6.	0.686
APP	REL	ENSOCUP00000009130	ENSOCUP00000004298	Gamma-secretase C-terminal fragment 57; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...]	REL proto-oncogene, NF-kB subunit.	0.416
CHUK	ANKRD6	ENSOCUP00000031319	ENSOCUP00000003910	Component of inhibitor of nuclear factor kappa B kinase complex.	Ankyrin repeat domain 6.	0.601
CHUK	ENSOCUP00000046340	ENSOCUP00000031319	ENSOCUP00000046340	Component of inhibitor of nuclear factor kappa B kinase complex.	RHD domain-containing protein.	0.840
CHUK	IKBKB	ENSOCUP00000031319	ENSOCUP00000006175	Component of inhibitor of nuclear factor kappa B kinase complex.	Inhibitor of nuclear factor kappa B kinase subunit beta.	0.999
CHUK	REL	ENSOCUP00000031319	ENSOCUP00000004298	Component of inhibitor of nuclear factor kappa B kinase complex.	REL proto-oncogene, NF-kB subunit.	0.864
CHUK	TNIP2	ENSOCUP00000031319	ENSOCUP00000008641	Component of inhibitor of nuclear factor kappa B kinase complex.	TNFAIP3 interacting protein 2.	0.445
ENSOCUP00000036387	ANKRD6	ENSOCUP00000036387	ENSOCUP00000003910	DIX domain-containing protein.	Ankyrin repeat domain 6.	0.678
ENSOCUP00000046340	ANKRD6	ENSOCUP00000046340	ENSOCUP00000003910	RHD domain-containing protein.	Ankyrin repeat domain 6.	0.661
ENSOCUP00000046340	CHUK	ENSOCUP00000046340	ENSOCUP00000031319	RHD domain-containing protein.	Component of inhibitor of nuclear factor kappa B kinase complex.	0.840