| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| IFNAR2 | IFNB1 | ENSOCUP00000015936 | ENSOCUP00000020497 | Uncharacterized protein. | Interferon beta 1. | 0.986 |
| IFNAR2 | IFNLR1 | ENSOCUP00000015936 | ENSOCUP00000026487 | Uncharacterized protein. | Interferon lambda receptor 1. | 0.923 |
| IFNAR2 | IL10RA | ENSOCUP00000015936 | ENSOCUP00000027490 | Uncharacterized protein. | Interleukin 10 receptor subunit alpha. | 0.629 |
| IFNAR2 | IL22 | ENSOCUP00000015936 | ENSOCUP00000001423 | Uncharacterized protein. | Interleukin 22. | 0.728 |
| IFNAR2 | TP53BP2 | ENSOCUP00000015936 | ENSOCUP00000003994 | Uncharacterized protein. | Tumor protein p53 binding protein 2. | 0.926 |
| IFNAR2 | TYK2 | ENSOCUP00000015936 | ENSOCUP00000036146 | Uncharacterized protein. | Non-specific protein-tyrosine kinase. | 0.986 |
| IFNB1 | IFNAR2 | ENSOCUP00000020497 | ENSOCUP00000015936 | Interferon beta 1. | Uncharacterized protein. | 0.986 |
| IFNB1 | IFNLR1 | ENSOCUP00000020497 | ENSOCUP00000026487 | Interferon beta 1. | Interferon lambda receptor 1. | 0.920 |
| IFNB1 | IL10 | ENSOCUP00000020497 | ENSOCUP00000019534 | Interferon beta 1. | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] | 0.753 |
| IFNB1 | TP53BP2 | ENSOCUP00000020497 | ENSOCUP00000003994 | Interferon beta 1. | Tumor protein p53 binding protein 2. | 0.887 |
| IFNB1 | TYK2 | ENSOCUP00000020497 | ENSOCUP00000036146 | Interferon beta 1. | Non-specific protein-tyrosine kinase. | 0.936 |
| IFNLR1 | IFNAR2 | ENSOCUP00000026487 | ENSOCUP00000015936 | Interferon lambda receptor 1. | Uncharacterized protein. | 0.923 |
| IFNLR1 | IFNB1 | ENSOCUP00000026487 | ENSOCUP00000020497 | Interferon lambda receptor 1. | Interferon beta 1. | 0.920 |
| IFNLR1 | IL10 | ENSOCUP00000026487 | ENSOCUP00000019534 | Interferon lambda receptor 1. | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] | 0.468 |
| IFNLR1 | IL22 | ENSOCUP00000026487 | ENSOCUP00000001423 | Interferon lambda receptor 1. | Interleukin 22. | 0.416 |
| IFNLR1 | IL22RA1 | ENSOCUP00000026487 | ENSOCUP00000005829 | Interferon lambda receptor 1. | Interleukin 22 receptor subunit alpha 1. | 0.690 |
| IFNLR1 | TP53BP2 | ENSOCUP00000026487 | ENSOCUP00000003994 | Interferon lambda receptor 1. | Tumor protein p53 binding protein 2. | 0.922 |
| IFNLR1 | TYK2 | ENSOCUP00000026487 | ENSOCUP00000036146 | Interferon lambda receptor 1. | Non-specific protein-tyrosine kinase. | 0.965 |
| IL10 | IFNB1 | ENSOCUP00000019534 | ENSOCUP00000020497 | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] | Interferon beta 1. | 0.753 |
| IL10 | IFNLR1 | ENSOCUP00000019534 | ENSOCUP00000026487 | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] | Interferon lambda receptor 1. | 0.468 |
