STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRUNE1Prune exopolyphosphatase 1. (450 aa)    
Predicted Functional Partners:
HDDC3
HD domain containing 3.
     
  0.900
ENSOCUP00000041459
Uncharacterized protein.
     
 0.818
ANKRD40
Ankyrin repeat domain 40.
      
 0.680
BNIP2
BCL2 interacting protein 2.
 
      0.628
CYFIP1
Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.
      
 0.615
GSK3B
Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily.
    
 
 0.601
IP6K1
Kinase; Belongs to the inositol phosphokinase (IPK) family.
      
 0.598
NME1
Nucleoside diphosphate kinase.
  
 
 0.588
THSD7B
Thrombospondin type 1 domain containing 7B.
   
  
 0.570
SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
  
  
 0.542
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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