Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
TMPRSS11FTransmembrane protease serine; Belongs to the peptidase S1 family. (438 aa)    
Predicted Functional Partners:
TMPRSS4
Transmembrane serine protease 4; Belongs to the peptidase S1 family.
  
 
0.794
HPN
Hepsin; Belongs to the peptidase S1 family.
  
 
 
0.683
SPRED3
Sprouty related EVH1 domain containing 3.
      
 0.560
RIT2
Ras-like GTP binding protein.
    
 0.523
F10
Activated factor Xa heavy chain; Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting; Belongs to the peptidase S1 family.
  
 
0.518
ACE2
Angiotensin-converting enzyme.
    
 0.516
PSMA5
Proteasome subunit alpha type.
      
 0.490
B3GNT7
Hexosyltransferase.
     
 0.484
UBA6
Ubiquitin like modifier activating enzyme 6.
     
 0.473
CTSG
Cathepsin G.
  
     0.472
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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