Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC100353137Uncharacterized protein. (195 aa)    
Predicted Functional Partners:
IFNAR2
Uncharacterized protein.
    
 0.773
IFNAR1
Interferon alpha and beta receptor subunit 1.
    
 0.668
IFNLR1
Interferon lambda receptor 1.
    
 0.520
IFNG
Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family.
   
 
 0.470
IFNB1
Interferon beta 1.
   
 
 0.467
IL10RB
Interleukin 10 receptor subunit beta.
    
 0.459
TP53BP2
Tumor protein p53 binding protein 2.
    
 0.459
G1U1Z9_RABIT
Uncharacterized protein.
    
 0.459
IRF7
Interferon regulatory factor 7.
    
 0.422
APOBEC3A
CMP/dCMP-type deaminase domain-containing protein.
      
 0.419
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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